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Zomacton 10 mg



Príbalový leták

Príloha č.2 k notifikácii o zmene, ev.č.: 2012/03710

Schválený text k rozhodnutiu o zmene, ev.č.: 2012/04490

Schválený text k rozhodnutiu o predĺžení, ev.č.: 2012/06225

Príloha č.1 k notifikácii o zmene, ev.č.: 2012/09327


Písomná informácia pre používateľa


Zomacton 10 mg

Somatropinum

Prášok a rozpúšťadlo na injekčný roztok


Pozorne si prečítajte celú písomnú informáciu predtým, ako začnete používať tento liek, pretože obsahuje pre vás dôležité informácie.

  • Túto písomnú informáciu si uschovajte. Možno bude potrebné, aby ste si ju znovu prečítali.

  • Ak máte akékoľvek ďalšie otázky, obráťte sa na svojho lekára alebo lekárnika.

  • Tento liek bol predpísaný iba vám. Nedávajte ho nikomu inému. Môže mu uškodiť, dokonca aj vtedy, ak má rovnaké príznaky ochorenia ako vy.

  • Ak sa u vás vyskytne akýkoľvek vedľajší účinok, obráťte sa na svojho lekára alebo lekárnika. To sa týka aj akýchkoľvek vedľajších účinkov, ktoré nie sú uvedené v tejto písomnej informácii pre používateľa. Pozri časť 4.


V tejto písomnej informácii pre používateľa sa dozviete:

  1. Čo je Zomacton a na čo sa používa

  2. Čo potrebujete vedieť predtým, ako použijete Zomacton

  3. Ako používať Zomacton

  4. Možné vedľajšie účinky

  5. Ako uchovávať Zomacton

  6. Obsah balenia a ďalšie informácie


V tejto písomnej informácii "vy" znamená vy, dieťa alebo mladistvý vo vašej starostlivosti.


1. Čo je Zomacton a na čo sa používa


Zomacton obsahuje liečivú látku somatropín, známu aj ako rastový hormón. Rastový hormón sa tvorí v organizme prirodzeným spôsobom. Zohráva dôležitú úlohu pri raste. Somatropín nachádzajúci sa v Zomactone sa vyrába vo farmaceutických výrobných zariadeniach.


Zomacton sa používa na dlhodobú liečbu u detí

  • s poruchou rastu v dôsledku nedostatku rastového hormónu.

  • s poruchou rastu pri Turnerovom syndróme (genetické ochorenie postihujúce dievčatá).


Zomacton sa používa aj na liečbu u dospelýchs potvrdeným závažným nedostatkom rastového hormónu, ktorý začal v detstve alebo dospelosti.


2. Čo potrebujete vedieť predtým, ako použijete Zomacton


Nepoužívajte Zomacton

  • ak ste alergický na liečivo alebo na ktorúkoľvek z ďalších zložiek tohto lieku (uvedených v časti 6),

  • ak máte aktívny nádor (rakovinu), nepoužívajte Zomacton a oznámte to svojmu lekárovi. Nádory musia byť neaktívne a pred začatím liečby Zomactonom musíte mať ukončenú protinádorovú liečbu.

  • u detí s uzatvorenou epifýzou (to znamená, že rast kostí je ukončený),

  • ak sa u vás zhoršia problémy súvisiace s činnosťou mozgu (poškodenie mozgu),

  • ak ste vážne chorý kvôli komplikáciám po otvorenej operácii srdca alebo brucha, po viacpočetnom zranení pri nehode alebo pri náhlom zlyhaní dýchania,

  • u detí s chronickým ochorením obličiek v čase transplantácie obličky.


Upozornenia a opatrenia

Liečba Zomactonom sa môže uskutočniť len pod dohľadom kvalifikovaného lekára so skúsenosťami v liečbe pacientov s nedostatkom rastového hormónu.

  • Zomacton obsahuje konzervačnú látku, ktorá sa nazýva metakrezol. Vo veľmi zriedkavých prípadoch metakrezol môže spôsobiť zápal (opuch) svalov. Ak pocítite bolesť svalov alebo bolesť v mieste podania injekcie, povedzte to svojmu lekárovi.

  • Pacienti s Praderovej-Williho syndrómom sa nemajú liečiť Zomactonom s výnimkou prípadov, u ktorých je tiež preukázaný nedostatok rastového hormónu.

  • Ak sa vo vašej rodine vyskytuje cukrovka (diabetes mellitus), lekár vám bude pravidelne kontrolovať hladinu cukru v krvi.

  • Ak máte cukrovku, vaša liečba si bude vyžadovať dôslednú kontrolu glukózy v krvi a možno bude potrebné upraviť dávkovanie na udržanie cukrovky pod kontrolou. Lekár vám povie, ak to bude potrebné.

  • Ak je u vás nedostatok rastového hormónu spôsobený poškodením mozgu (vnútrolebečná lézia), budete pozorne sledovaný, aby nedošlo k zhoršeniu alebo opätovnému výskytu tohto problému. Ak sa to potvrdí, lekár vám povie, či je potrebné ukončiť liečbu Zomactonom.

  • Ak ste boli vážne chorý, napr. nádorové ochorenie, liečba Zomactonom môže spôsobiť návrat choroby alebo jej zhoršenie. Ak si všimnete akékoľvek príznaky, ihneď o tom informujte svojho lekára.

  • Liečba Zomactonom môže viesť k zníženiu hladiny hormónov štítnej žľazy, čo je potrebné liečiť. Kvôli kontrole vám lekár urobí testy, aby zistil, či nemáte zmenenú činnosť štítnej žľazy.

  • U niektorých detí, ktoré trpia nedostatkom rastového hormónu, sa vyvinula leukémia (zhubné ochorenie krvi) nezávisle od toho, či sa liečili rastovým hormónom alebo sa rastovým hormónom neliečili. Nie je preukázané, že výskyt leukémie sa zvyšuje u detí liečených rastovým hormónom, ktoré nemajú predispozičné faktory (náchylnosť na vznik choroby). Nebol preukázaný žiaden vzťah medzi príčinou vzniku choroby a účinkom liečby rastovým hormónom.

  • Ak trpíte ťažkosťami po operácii, zranení alebo vážnymi problémami dýchania.

  • Ak si váš zdravotný stav vyžaduje operáciu, boli ste vážne zranený pri nehode alebo ste vážne ochoreli, lekár pravdepodobne prehodnotí vašu liečbu.


Ak sa u vás objaví počas liečby Zomactonom niektorý z nasledovných účinkov, kontaktujte ihneď svojho lekára alebo najbližšiu nemocnicu:

  • opakujúca sa alebo silná bolesť hlavy

  • problémy s videním

  • nevoľnosť a/alebo vracanie


Prosím, kontaktujte svojho lekára ihneď, ak začnete krívať alebo pociťovať bolesť v bedrovej oblasti alebo bolesť kolien.


Iné lieky a Zomacton

Povedzte, prosím, svojmu lekárovi alebo lekárnikovi

  • ak ste liečený steroidmi v dôsledku nedostatočnej tvorby ACTH (adrenokortikotropný hormón). Je to preto, že počas liečby Zomactonom sa zvyčajne musí upraviť dávkovanie steroidov.

  • ak ste liečený vysokými dávkami androgénov, estrogénov alebo anabolických steroidov (anabolík), nakoľko tieto môžu znižovať prírastok celkovej výšky.

  • ak ste liečený pravidelne predpisovanými liekmi, napr. steroidmi, liekmi na epilepsiu alebo liekmi na potlačenie činnosti imunitného systému.

  • ak užívate inzulín, možno bude potrebné upraviť dávkovanie na udržanie cukrovky pod kontrolou. Váš lekár vám povie, ak to bude potrebné.


Ak teraz užívate alebo ste v poslednom čase užívali, či práve budete užívať ďalšie lieky, povedzte to svojmu lekárovi alebo lekárnikovi.


Tehotenstvo a dojčenie

Zomacton sa nesmie používať počas tehotenstva a dojčenia.

Skôr ako začnete užívať akýkoľvek liek, poraďte sa so svojím lekárom alebo lekárnikom.


Vedenie vozidiel a obsluha strojov

Zomacton nemá žiaden vplyv na vedenie vozidla alebo obsluhu strojov.


Zomacton 10 mg obsahuje metakrezol.

Priložené rozpúšťadlo obsahuje metakrezol. Ak ste alergický na metakrezol, použite formu tohto lieku bez obsahu metakrezolu.


3. Ako používať Zomacton


Vždy používajte tento liek presne tak, ako vám povedal váš lekár. Ak si nie ste niečím istý, overte si to u svojho lekára alebo lekárnika.


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" name="Obrázek1" align="left" hspace="12" width="53" height="194" border="0">áš lekár alebo zdravotná sestra vám pomôžu vybrať si najlepší spôsob používania Zomactonu. Tiež vám povedia, akú dávku máte používať. Liek sa podáva injekčne pod kožu bežnou injekčnou striekačkou alebo bezihlovým aplikátorom ZomaJet Vision X.

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" name="Obrázek3" align="left" hspace="12" width="53" height="194" border="0">ávkovanie

Nedostatok rastového hormónu u detí

Zvyčajná odporúčaná dávka je 0,17 – 0,23 mg/kg telesnej hmotnosti za týždeň. Táto týždenná dávka môže byť rozdelená na 6 – 7 dávok, čo znamená, že dostanete dennú dávku 0,02 – 0,03 mg/kg telesnej hmotnosti. Maximálna odporúčaná dávka za týždeň je 0,27 mg/kg telesnej hmotnosti, teda dostanete injekčne približne 0,04 mg/kg telesnej hmotnosti za deň.


Turnerov syndróm (len dievčatá)

Zvyčajná odporúčaná dávka je 0,33 mg/kg telesnej hmotnosti za týždeň. Táto týždenná dávka môže byť rozdelená na 6 – 7 dávok, čo znamená, že dostanete dávku 0,05 mg/kg telesnej hmotnosti za deň.


Nedostatok rastového hormónu u dospelých

Počiatočná dávka má byť čo najnižšia. Odporúčaná počiatočná dávka je 0,042 mg/kg/týždeň. Túto dávku možno postupne zvyšovať, nemá však prekročiť dávku 0,084 mg/kg telesnej hmotnosti za týždeň.

Dávkovanie môže byť potrebné so zvyšujúcim sa vekom znížiť.


Návod na prípravu roztoku

Zomacton sa dodáva ako prášok a smie sa miešať len priloženým rozpúšťadlom.

10 mg/ml roztok na injekciu sa pripraví zmiešaním Zomactonu prášku s 1 ml rozpúšťadla v naplnenej injekčnej striekačke ako je znázornené nižšie. Jednotlivé kroky popisujú použitie adaptéra na injekčnú liekovku na použitie s bezihlovým aplikátorom ZomaJet Vision X a konektora na prenos rozpúšťadla na použitie s klasickou injekčnou striekačkou.


Rozpúšťanie pomocou adaptéra na injekčnú liekovku na použitie s bezihlovým aplikátorom ZomaJet Vision X





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naplnená

injekčná striekačka

šedý uzáver injekčnej

striekačky


biely uzáver adaptéra

na injekčnú liekovku

adaptér na injekčnú

liekovku


žltý uzáver

Zomacton 10 mg

injekčná liekovka





moRQMKgqskz/UBrEmFgE67px4vRTWlpalixc+Ltn/nT/Lx+afeasb1/z7eEjRviRl3XBB/KDPkpWe/fu/Wj16tdef33Zsg979a656trvTpg4KRwp1unSTfq9GU/Qv5gtj3Mw4zjiikD6DtPXtmUhij89YWKZ8bamKggRFUhQVQ3LKikpOefc82acOvPfH6xYuPCtSy79+rETa88556xjJ07o1asXpVrIZUL3Uh2ey9zx5rBQiZQ6Nm7a9Oorr/7jn29TNB1Te9yN3/9RTd/+AS1MkUHJjZ5vmnbCYOQHEeyglhG7KBF6gKJPQpj9ZRRnY2LSUwjRAqoEgSIjCSmmZVPGD4fDU086ZeJxx+/etX3limUPzX0EQTx96vQLLjx3zJgx3Zf6/KEHikbDMDZsqHvqqadfe/2Nsope53z5gmknzVADYcM0Kc+ZhoEZSoCeMEzLotKNdLwCBQkIVc0/hlyTEGJhW4aSZVsQKcS0ATBCgYAQkYpMOZuyOrYsOxgKDhg8dMhRI8694NKlSxe/9vKCZ5/9PZWJ1173rbFjx6iqSo8UD/sQps+hIDvo85QmZcC6uo2LF7+76N3FW7ZsHTx01E03/3jUmLGhUIQizrQMegjBjvbVdSr6MdULgJFacuCHEiP7gxAQhgw9huGSMrjErmHbSFaopklAI6BQxgRcyQCKP/pXIkxoUjwqqkTZ+fjjp3z66doVy9696Xs/6Nu39/SpU6dPnzZ69Chx8UxIMpuyj97Htm3bb731tmjMPPX0Wdd+53slZRX07uhqOVsGiKMKMeVJhmqhHsS5ncJmxP2G/8Wu6dNOKdA92+ImnviUIlGltAzZ4+DWD+V1EgqWTZs29cQTj29rbVv+/uLX//rm66+/8cgj84YMGQxcM+jwIFP0eXQn3u7cubOpNfr4E88gWbWMBKbsBbguFe4GWxW9WYlzpQx8xi3utACPszhIFBsuioWjwh4AwkBR5WAwoDLVTGUA/Z/EnwWjb8Q1D3GMRnYBXFU+fNjXL51z2dfnfGXb9m0cfSgTeZh9zStLSmtbQjfa6J0jItkA+0w+4Ydxt4GZJdwVYW8Q6MS8HT+BHS9BgIdFhuc2yFEGAUxh57HvmOx0vRkQCgVkReOyV/zr7Nh0ebGHfWZnoOugxmo0Ftu67bNIpIyyjdDGnPUQ4OTC7hQS4vO6+JmknVc9YoDYf/HONgeXoD600h9jwiHZI2baGpgSlugRzAeEoHF/oqmxkSoQfhZI6Vl3EbKJPnq7I0eOnDVz+mPz7qduKBf57M6oV7B7zx4tGOHeKGdX0kGK8ZPTXkJXlCZVMdQ1rK6qCkdC/AMuKDCeNnUyVR3iSWbiy2WZeUtLS2+55ZYrr6xndi7ktACktWvXX3fTzaecckEgUkTtD0kQX0caEdB5HWmlYjqKS/bWiEf/9soz37z6ilNOPhlwScipE1ZUlFML8bCX6UE2DRfAV0tvKxQKc3ISehY1NTUEZHD6yeN69+5DGdiTacyIEcAsYWyTDtwqce5ldgi/ujDq+FtmoiBupzB9gfhfbqmLS2HsXpaQpqamRW88XVFR1W9QfwgE8SfReaeoVjqQHa/Db0x49yeCSfSFogQQwSVhrao0zM8QMslDHuUwumQWAvCuRpjhxi/I0cTQJzHhhTja6GuOTMQtZcSVLuRYY1enzoewQJm4xAn6H01ThbggTgzRDxn5ITnyeT2cMhqkQpouyMQmN2OEsgMu6pgGwHzZwrjw1IoQS1xUcv+NiFAV+1TgiTpxTBVxAcupz7HbsYs7+t5grhzRQioUD9UJ5HCxzJQ26USM6UF27L6DfiKpLL4EbcPqIJncw8UpBNpQrK/9bKGleVjPf8121ewgAyYhQBhF3NXjlIgVKeAejDkHeyfAw9caHPIRcVEUhfIX4888AwQsioBxgPnFDLj1k81fyAf6KPPKskxdXtdszh9YlkXRp6oB94Msx6zygT4h6elKQGYO5mGAQB99eDm6fp7QRxdQAObl6KN/Nc2hPuipjixB/piXryTLoic1eOKBQBHBFqHmjt9lB/JGfYJ5PSsh1xLQyRHTH+VpTDe6Aw8/OpAS8oE+lh1TFMFHHPKnPQzDoGqXkr8bW86y5M1Tpk3tgL78ATVchE8i3mZddOQJfZT66ErEa+IF63IGnnluWbaQvDn6oTyhLxgKUT4Sr4X6y09Vq2WZModcZClBPqnPYhk1mM9SYIov+qMyT7HnAncgf+iTZY95QZpRvMMAL/BHSZ4afZIksp5HJvWxfLYW9Jg3n0CpT1FU/52ArBYK5Yv6VMVHfbx6JS9sTH+U2i3er2b9R/OlOjSNUh9MEa3MLei6HgyGBOKyTnogP+ijd6yqAb2defOHQUp9qqqA5BKcrEGeqI+qv3hCpD7sQx+dPaCyLxQM5u76eUJfKBTaX9+Ya3MvKexMWPmWKfK5IAelpSBv6NM0ja7EX9SUO/DEHODU1zHUfKQyr1/z5hb8ioI+s9LSEoG4I5X6uN0XoCtxSpZzT4AeUOpTfXZf1iFv1CeL9Gt+fs4DzrxHOPoouQW43Sfe5g6JxKsZcMvmTMMUdl+OfjFP1BdQ1fzE+9wKBucJ2bblad5cQP6YNz+pIs88FhRHBW44HPbXfoAj0eelHCQy1vnUGzxgZSvteSIGR57TRkGSJa8eCORe+XosTJlXYQ007d0T2f2h/Mk+zIHXkuUcPNPPNG1qsR/xqkNRZL4cajnL+ch1iFpwXkiqqjlcY16ZV7zOaa5DFLhB4oQUud2nec7ikcq8Gl8D66rKMfilqhAXokIjR08rf4YL4FYYACohJLfMS9wmdf5GlmQPp0eq4SLumNouXpFOLjWvZzNTUQvVgJpk92UR8oQ+Uckt1pPzaLM7MUEY6rIs+vRz8sDyhT7JQZ8bSspxopI32gh0iSxlUvNYtiDf1Ef/S3GYnx9NKu4DR6jZTFgDIEOfWE9ahksmUU7MOxIF9eUI8hSw4s25gPu8yBdYOjQITk8Pha6iEC62Fz44gu0+yryiwFQ0BQnq45ag8y0lUN7g3aGlygVnWIv4mwTeV+396KxVk7V+uNVpKEcFLiB/hgub5GDff/8DoVBIJMAAFiNHiChZPJBF7cb3gb8X2vchH3pDbKYrkAQIvSyilp5EgKSohp6IR9tyWg6cH9mHi4oiX/3qxTt27Px89+5Fi5acc87ZLW2GqshaACV027TsVIs8hIkjSC2gSuGQRt80tyZs/kiaWtqqyiKvvvKXk6ZPmzp1imj9O6LNZhiJUPRdSl99+OGqnTt3XXfddbv2xYqCamV5pKElpusmkjsvqQt1yBgXhelFiqiY276rwbCwYeLtn38xcnD1kkXvnHfel2fPPgscqmkzE8jfCDC/0U+lGSa2RZhuxNiCEgooyfoxaZUp6ZBKTCpSCWbTDLgktZnYw147XHt82++3HWHU50XfXA3IAkqIiXYcTcSpRa2yzr5OnbxduTQRIyIYnWqqJitsDJHGIlTJbaZHdsigI4imSYoyZPPBIhB0xp576EFXzZr/2PAcDKlfI0NmqEgSnwDhuG1JTepHhuFyIAYRHXlehwq1VGSEdBOzNkpJdJ1CzDpLIXIxylvSIR+IQVIMKxGEx01DAm3TpMTHPWskfg76gy+5CPnlivoOFaFkH1I60QJqTI/Rw1Uksz5wAmUk5lg5w88s22kk5S2mHZQJN76p4YgBUiEbBGYaOtYtU7fslJ2mR57Z7Df3nQlfHLyxIIiZuMSg9rRhNzZHY/FEn97lIU1jhANNm8Bdu/eZBl82JUrUcfH8KmNH9QMhYtnEMjFJnoyIgA9rRwz1+dBE/Bj0Kuv9a3CSEmyoC0UY5iNX+BADQo1fYBvCc+Wo7xhrIG6rOUVSNGEaNmnvdIbtV/Zb2lmH/Gle4FsPdaXYED7WraWyuZk8oCDLpirTjwOqEmAo5HNcFDVADJuP/6JoSkq0M0lqWSSq46YWaoSrDH3YkhVJkdi6FEX2Ht4Ro3ndcB5KJOJ1dXVbt21jYUuON/r51q1b9uzZ++abb37REAsqSiisUm9BzExirbc2WbdGlhx1wLwxQ6c0Z7tDTJOpjz6KTz9WMBtUhIQaoQxf39i8Y2NJPB5fuvR9PaETdwAEPSAUDo8aNXJA//7ZWmwuqI+tKx5PzJ378KuvvVHVu69M1YGY48BzYJW9+r70lzdAshzrJJWYHKN4UaiByPWGxJwMgmEXBhCsXwOGDx+99tON69ZvdI9lBnZrWwu2jAcf+OWoUSO8gzPh61ygj2Fq7do1L73y6nXX/yBY1KshmmDcBFMNmPLO6WyUCPllIShjd/4U7ixVO57T2VcRVIxDIbl3ddngvlU//987Kbzwwnw+fe7Al+oaZB99Qj80NzeVlpSOOfqYD9d8Vr9397LFfydsECli02+5CEvGJQSuVnE/cYZfSTY2bZtI1DCEHe6287JJJ2eD4xzb2O4/eNiZZ54L+5KxR4996ndPUEGhqsi74cNebO7muEDkTLNBvasiaz56b+Dg4du3bLj66quLisJOWM4HnVfAbRCyefPWRYsXT5l6yvKVSwf16z9t6okQHZgAOz4AyurLV66s2/hZVWX11rq1yuwL2bgiApyRitlQxznUvHwCi01xSGkuoAWPmTBl144t1133rfLyiq7cuNCVS959b9Nnn11z3Q37frZ/0vjR3/3uDfxLMZz4gCEZT88++tjjugknHnvCokVv2chKOaAuE8gh+rjHhLg4YtEUyzbpsg3D6uIwBrFSXdcpEcUTCds2xWwgEZru4j3w2VjUKDf5/WS/PClHZjPq0LndcSR9VznGf07HIY+HpF1fWhK6oeqk4Gt2Cu17dkzICHrQlxH0oC8j6EFfRtCDvoygYOjzG72HcpsI6BgyOVC+MakQLQ8l/IVBn7ewrvqbvlghOHClnr9zw8Fgjku5CoO+pNzbgTCYRHEQJn+Y8ng/BrPtZSTDEUJ97Sd6tRmpyhJ80iAPnAu6v+pQFMUrAoI8KM0/Tj3MK0km5ihA74eCMa9hGIuXLNm1c5eYln6AkAus27ixob5hxfL3sY137Nj55/nzeZEgTN6xzDsDgOnTpw0aNAj8B6sOCtu2bbvnnl9UVPbSgiHiS8J5QMVWY1MjRdxpp5367FOPacHgxk/XLV+xcuy48ZgX+aYkrnXr1q5Zs/a+++7NyyIKhT4C1q+vwwQ9MPcRtmsHad/hyQMJwe3btpx7zuwrr7hi3rx5H676WE8kLp3ztTt+/L9tsURKlSBL0osL5v963kPf//53q6ur87COglHfokWLaycea9pWPK4DADozI0RSOFLct2/furoNFZUVlmVKMhoybFhjSwsfwpuigIOKyGOPm6QGtGXLlp9zztl5WEVh0BdPxJev+OCGm242EgnJ2dSusw1sh8KRkSNHb9q0icoyAlFQ0wYMGMyrKlkoGXQKl2JCevepqZ1w7JIlS8844wwxACenUBj0vfXWv6g27T9oIAZi+6FUVghhVd3jJ9SuWvlebW0tAqSstKyiupKV57OcECJePtwDXqR25pmzf//ME/X1+/v06ZPrheSluhS4kUpes0NZ7/HHfjt+/ITi4lKAhXmRupCUMuzRR49b/PY/+vTpTd9WVVVGIhFh1Xn1+b4TeU2MaY8ZO8Ywzbq6TS76cqiAcxmsdymDBYqRM7IfQbBx46blK1fM+cbVSJExD6OzJFyn+DtmZS32gEFDdRNroVBJSUm/fv01WeXlV2wnEL4bCCLEZ9/xfKZGWX7U6L/97W/TT5rKa9f4ThOiyRKg7LohuSpQA8JD4G9ZAR5riBFbaoCFixYPHDh09OixVH4hUTuQKgWM+GYKxcXF4XB4zSdrKOfW9O3HME4453IsEiy27yFOQRDf1YlKxWOPm/zovIfbWqOikJDvaAGchuKskmJumZfwXo7qXr0UVd25bROSpJdfeXXxwsUzTpsFoNTa2gbd7VtSbaXAKqYswzxu0uR5v/o1JeDxE45ra4tiwve+AtC/w5E4g9dhscv17T/AwvYLCxas+veqgCqtWL6kqqoXL/HK8gJzW2EFOPrKKytu+u735s59mNLgfb+438Zk9cerX3v5/9opLpUNLNphCGYllLFYVJGVH99+C9sRpX3Pto4lL6SDEKRG4k9/cjeja4SGDh16wQUXUncls805UkA+VAfVFafOPGN87TF6rJUuWTcsE2PL8pKWbNmdd0vz0GHarPSRsTLGqqwEgmz3D45x4m/uoi+KioIiF8mpHkZjuijnGjxgYFvC/vyLJpja2Tt8yBX6/EYF727ENX369e1dRhdgMaaEsbi+Z3+jcGxTZm1F+R5lR92wm5qjYvvoUDBQWhwSilfkITEkEkCsCgaDAX0rgpoiSCwW03fubnAbskBLrCnL89Y55Jz6PKJy1iEqb9nOOjiFrewD4nLaAcqku/CTHT/rtAF6FiAvZrNHA6m+IV2L+h0owlxYyAv6OgUv/XHNg1UdeOrB/6I7QbcIlx6c9Pzf5jr4ni4UGH1dZ97uCXmdpNHpw/aXnb/lpoxohmZvhXcrLD6Oc1FWX2DoFsx75EL3RZ/XCuLtfey+9Xb86KG+Ixy6Nfq8sB6AqQOCBYdujT7gRL2SesG9t4Xn3+6LPmcraTckz719gpwSAwDytV3PwaH7ou8g+iEPAxS7CN0Xfe3gjzp0M+v6SEBfcjF+N1Ij3R19nN7yur9WWpAL9CU3jxLga8R1MIGx5/+LHHknDAmxR3gLpZsM6kB1/ArsWxZJ5da1/wbEG8LDXFzhQGdPeeIdww7LcDBOTjoqvfiUG58U3bzOilxhZvNco/AqCOzcKOSsl/h33BZOh9u85nzAdyfnB7kf89/3IrIM89jZwRw4aWJfqWAmkBP0uZ6VeMLE3UIdOfkxwpKGvIFZECmf/dVpJV6LKhG5dEFfEGL3WO8A5+fEsAMnxsBTy0D0/kn8VyxB8sTpJ4Ke6dMNOyoZQIQkmfXi0tvjHeJiUgPkk6+RhMTEFXFoikCer3GNSBDa3POVIJLcydnEzZAzzLFmfmjzqURCQGBiSxJLBmOCECQykhQE6W0oMkoyGLtXP6/IUciy2tjQ9MnHnwQDZY3NcdPaTyXU1l37gmqAIpQixrDsRMLdsReSzhOrCN8Uiok2ttmfSTgr61YT6wnmAJ0Rsk7Gl77euacBOEhnlG3bfAwMH5RjQTtSFNm0deeaNWsjkYgYJ5N5nDFX/by1teNnnTbjgft+dvb5l+4Ml2BiO3KKzWoRQouwkg2R6u7cS+6AQ2f8JXSLZbwkrzgL0Yvz4CDiGIdu7py1Ugt9wqbrICJDqW79mi2b1v9q3kO8+KpDHfnhrTNH3eSkuLjojjtub2lpm//MI93E6qAYqqio+OUD902cOMH5JOP0Uw5ln6qqDz54/5133p67n0gXFEUpKop0SJ50S+Z1ACFUUVFecE+rffBd9x/C5B/VV3DEgY6K9QgYwpQ83aLQeMwiq3aGHNb3+V8UHHL0FHNeoNZNIEe31N0jLt0cetCXEfSgLyPoQV9G0IO+jKAHfRlBD/oygh70ZQQ96MsIetCXEfSgLyPoQV9G0IO+jKAHfRlBD/oygh70ZQQ96MsIetCXEfSgLyPoQV9G0IO+jKAHfRmBD33OICmvQhNYhDh1oWwSCyv96m7ttDkDXrfLSrP4CwcrGEEkifJWd9uGdvQRt+RLbOryUQP+zaaY2CdNEiWhIEUV3n8oEN+AReL05AB8alXgkkEBf02v3PEMBryUHW5ss57cbPBOHl6CJx7Bfwnx8Q1m+HqdCkFRVhhEEkMfp0Qxv60dfRwzGIjCTNaNTFjNOgFDgyikysCpcP8vAWfiFoAyBLaJ4foWmzgfCSw4XOhXHR5vEmc2GRuYReYeWzyulOES5nyMbzcCb78vSlItNpr0ZmOCz4pJKsdP0rxE8K7X9k4/KVbAgDCbI2iLbUtyd8dASJB8j8xwKta9104JMB+6xguB98Sx0w8B2A7UYtMpQWo+5vUP84EpFpBb3GFXfBDnx/NK6IzY+BaijkZF7jRf6DaneC8I3zQtBfMWFKDoPZKgszWYBWCe7s0rzHdkVjoyqtugjwH0xA0B2d9X6MDgdnN5W2h2+cxugz5n6gjMTrNUOsAad/gWhHyUoGDirt5Bd0EfFT6GDVsse0cc9w6gGk3Km/CjuCPEbLWkepNt9tsnBDS38+aQkLet3V3WZF4M4lMeER+aC1pMvLEFf9xkLWuwGnRyzVB1dLGaT+8mYeM/bLFe2hH/oNHqo+JnppRMKJe62DJceOprNsmqRuuF7eZ79cYp1eq0XoqG8trurGOwYIfxrz2U9mAIsU2Au5fsE940xnC/TlpMu9m09hlkU4u9ugmvbjQ/bbGiFpEleNnAwIMTIgEk4hOg81TrHEEAon1xa2ZvZfF+AwEZtrd7HRryQ31Mn+o2/t6H0VVNRpMJmg0Yty3mBQlbBYLLB2t3Hx0sVaArvPMHQQksmFYctcDMd2yxMbU/YHBwyAv18T6ZoAy/NiT8wuK4ZUvuPu0s8iMh8I1ByuPHFnHTz8Z8T22UzxktEAwrUjY028Q2gayw2z34XEsf5AN9iHfzUHwMLyLDIur6FguIJm++ieplA5S7j4m4t8tkNtuhMY+6w2ktZ/3CivNYu5fZzHu03tptXvdB27YYD+pA8X98fIXyy9pIRUDi793NiLnnmeX53gcBr229y/aKBznoaQNi/2J3cgOBTSZ5ekvinrXx/YapQFQTlD+PUZ8M1pbIL08vqQg4oyLaLLI3ThIEhCTYNwQUZ2cngUUbO6OEIHePnchQVppdoC9qAIkTNCio2exMbGATLrZErdtWx1/ZpVO7QEXq94ar5w4IXPRuVIb4oYnB6oDTtrWlDd+9Jv5eg95mgVJFOrFKuvao0NHFiA86YLEe1D7EnXt1juueBfQJshdzJzCU0uojy0VHJUA8zkplW4OOv/ZedFk9RSPuF5R+Nzl8Wm+qGaSHJgT2J+D06gBDDMEtGJy5qGVDK+aSG+/Q0SfN5vwtzXeMC944PMB2egKc+OgaMZeKmP5BGGZpfCQz3qVeGvzx0WEVwgGhNHCSffRxhYoo/lbsN6/5d9vHjTaA0qm9VKofJpbLIr5xfj/NO1jH8Ccfx+taiNSyN/LavKL9W5trRulTLmzqN/LmVbEFO8xrhmqza+SKAPSGjXhEmBUQE7TLVfA/R6kApMW7uWBebpW8X29evSK6oZWSF/7aoMD9x4Srg0jMD+cjMjAjKd5eu6LB/vOOOEFIWfj89LYXbrvp6D/+bdf8X30rcdwZ8VnXLJf7rPmg5ZkK5c6xwRnVChC5K3YqG/KQpRAkAt5eXcSJ0+fNcPEFh4mTUNrcal2zsrWuxZYhvGJo6IHacJHKJ94QPhgD8tEiPEBqWOR3m+Ofx5G097OaT1++8+b4xDFLJ40+5txTpj7w9NLVjyyrP+3b8aNnLCJo6TtNVwwK3TAyMDKiyByFyMmsQkeNuwMjDgOEdmKChJlMkoj8dOXETNHnRNiFscETVNSBnfN+2/pm9u01w7QfHx0qVqDzQ+w2EV8tFjOV3tlnv7jToJqg6JW5Fxyzbcxwg6leuGrG+E3jfj76zfdrnnn5dx8ufSk+/SKj9vQnt1pv79Mv6he6epg6JOKNeWHLZiNwgJedOAxw7jBd7GdMfdyMsHgumL7bFQfX/zuxvoXx7HdGROZO0NCB19Nm4auXNbdhJbDypX6fvXnVTQkWKeI7vhCjrUJbPmfm6ktnn/XIH8rmPvuj6Nt/br78ri01I+77NP7HrfrPjgl+fUhApBM5NwvqzmeOhEHG6OOZUIkXI1An9mdroiv2G/TNRQOCd47RJO7BEoCSFkU1p4XJveuMXXGI7JbghvdIKLBiTay8GFUUY2g79AythNT24g2XDJxx/KTfLWj5x1PX7xg5w5hy4efV/a9cHn1uS+K64dppvQMRhVsd7HfyncXPnPqAm5OHc9fHn9mSoIQ3ukS+75hQdYBtr5OS+CjK4zZJYGZyEVlrufCOxLrpt77w2Pw31n9nTmzm5ISC22feQHPbmL57fnFjr0s2T37s+TWvz3tTP/G8xMxvvF0f+XB52wkV+h1jtEmVKoIk65MeDgmZoo+7FhLA+O0v9B9/FNch7KOhV6cXDwxzyxn68NsRwir5ZW3w/H7qHR9HlzWE45PO2T36hNa//nbl3a+eP23fDy9rrqnGCuJzvdg/PQC2n3DU51PumvzykskPPf2XDavebD77pqbRU/66Fy7Z13rtUdqNI7RqDcndF31OcQJwAiLACyzBPXFy79p4AtilMvr5uODQiGNRuAOXUl6OHXNCFXphavFfdyZ+u8VYRspbL/xRfPI5zy1esOTWNy6csm/OWfGjBprEYNqBIdG2CF569pR1x4465tV3Kv/0j4fXvPeifvLXWocfd98G49XPzcsHBy4fpNVQCYrErTlK2b1N3FmMZAjpUR8RU/gYP/Lhcljihgiav1N/5ws2setL/dSLBwS84w9ys9D9Wx5Alw4Jfrmf9vQW/c5PYm39RlqX3bVh58XzXrh7wT9X3nh59MrZMZn+osU2hmGnWI19w4u/fV7gwllf+vV87dFHrgmMPzl6wa3r5X53fpJ46jP9F8eEzu2nttdTsNFzMnaGWblZ5CxB+szLHqjtaHp+O5tbbEp6mODeQXTnaC0kd0l+u/l8diEFwqIAuXFE4PQ+8sMb4m/sMnb1H9t0/ZP68ldveeH515d8es35TVNrjXCAIIz4rEgMrHiF9spd3xw+e/pJj/5x56LHvrm3drYx+ZzNuOaSpa3n9FW/c5R2QqWsseAxcnK3WFTuZFM5p40+Xq8muTYlNm148+roFwlMkTZvQvGIYgl0zenxktPQ5W/6b3SRMncimjNIe3Rj/MUdSuLEC1HtzLeXvbb6sWen9t52zZzY8eN0RkjC9Ca2bXw6cdjWh289aum6MY/PX7L40Tf1qRfFT7z4pc/x0n0tp/VSbx4dPLpUdkosIHAmdhaE+sRqEbt5MQyUWlzo7b3Wwr0mxcWX+shn95NTzTE8wNVEGSFzPojYn45pCEg0gKZWoWmVyuuDjNs/at2ASuKnXbVn0hmvvfjgwjv/+Y1ZTTdc1lweoSqFOge8oMNKRKSPzxi/Ztbk0559fdSDT/5q7/KXm8//0d5h457bbvxtt/nDMdpVQ7US5m0jmO0oYhroc+kFiTf0ddQCf9qWaDVIqQq/MVQL8A37ulKI5TlEsL02x3O7xEBDMLtGrS0vfWmb+fTW+Cekuu3Ke40N5z28cP6b33/nslMbLpqZqKkCxHL4ktgYxf9+xaya6eOPeeHvyoJX/t/GipHmSZfWDxr3w4+MBdvMbwxlQrlMRc7PZgnSYV53gcjZGRxujdlv7jboZ7Vl6oxqmcfgUhkpKS/W8ShXyfAyHScQRWo06foR8nn9lcc3G/esbTWOmmQedezH6z/46Wu//ONrq753pXHeqTEWX8dOnAJYnw+u2HvLnLILZ5368J/a5j9yrT75S/FzvvtBW/maD2OPb9TvmaDN7BUQxjwSgfnMdElazAucKgrivH9yU7zesBCSrj1KKZIlN3pwaNmX6msXfx7789+hsqJfCP3s6NCF/dV710b/ucdoHD2lafBTny5+/vqn/vLakk03XdI8epgdljAWZXXYRmj/sKr/e+T7486fefyjf/jg/V9+tfGkOXrtrI9I5UWLE5cOsG8dqw2JsP1rIXH3oOk6FjpCOszrzQwloNHEDSZ5botJFzihVDqzj1PxC7ObYmQPwtn+eFyp9NtJRUv3G7+u0/++NxI9/Wq99kuvLHtx+d1/njV697cuNsaN1KEh9g6k9GgjfdUpYzaO+3+jFn844vGXXlq5/DX9pDnR2tOf2IqXN1jPnxgZUezT/YdLfmkxL3FiUpB81Gi+vNNosGyI8S2jgsw+cALCWZPNokKThfXE5kQYFinwjD7aqb3V57eZ31/VXF9ZEzvv5q1Tv/rH+T959aaF11/acu35bRGNIAuxiA6LJbSVKyvPm7ry9KlnP/FC9dwnftC68i8tc+75hJQ/vjlx3zFBme2RnFGgIT3DRTwn0ybv7rP/tJWao2B4iTq1WhGV5zC92rgu/JjDXHz3XmSLGJeCwGWDlGlV5b/fqv9xi15XXtXyzQf1tYt+/q8/v/n+iiu+1HDmdLOqiI0gFoFVYIKg9Pp3Lxl0+skn/vjB/X9f9mLszP9Z12w1W7BS6YqkORikJfsccyWB4aJ9ZoNBbxBMrZLKFFenEI/Ds5EAIyJU43qGRFROApHhGBCGPxqtfWWA9qu62G8/s/RxM4zRU5evfufT5x/+/ct1N1+pzzwxLtsOt7A9kM0tY/o3FYXHYZazg4Q4sW6ezkq1PXDXIC3DxQmK7k/gjxpturaQRKZVqUHZMWWyXFHrtJ74t5Zsvzxii0ZHFZGHJ4YuGhD46drE+/tIdNKZ+sgTVrz95JUPv3He4u3XX9w6tL+t8bgDUMA/3on/bX3MuuZ0pCfGlmklqnvbGbBMml4H30D4nS+MBoM9tFIZjSstXKMMZ2wEIeWA+VNC7+wNzNsYf5+URM/5XmLi2X94d8Hiu14597h9V54fG9bf2r5Hvv1X4eiUC+yqYRUBfPVgzfVFMoL0DBfAK8hf3RkXRnRNGA0vVjO8g8MGUa3NQ3yoPAAu6C+dVaM8uUn/4UeJeL9hsSt+Xrf9kl///qfPvb7i1m9H9+yVN8HB8VMuox7wz2pLRpVSE0fsmI676GWmhLSYl7FuiwWW1XM9S8AJlUpIynuA3IX2fDZx2i00CVw3Qju9Rnm0LvbSjvjO3ke13vAb68O/3/7G88Gm7fo3fkq0yGmV8OpBiMURIHY3Bzj8+0+H+rjg29Ri7tWdVNS0qpw2KxwKoNsq1r5+tr378CJ07/jwFcPAg+uiC3YGY8eflxhzUnR3nTV0YqVs3zQihESONBtmQto+75pmtrk8e3yQTCxTMvz5TMDJT3LlitoNA3Z3mkzGl5Cnji+6eJd++5roRliaKD4BWPasPspJvVSRXEKOc0jyxLzi5uraqL1CihRQpUl9QjADhycLwH8bJWllV19DalCd3S9wbJX62o74o5uMz6LwlpFamFVjog5HZgBpR5u3R5nUq1CkUSVyABWgjyAtoHTVOwCvGho8v19wY5tBPb+CBawoqcdMvDfBot5lATg8ArNu6mUfuCdEb7RMI5M1hW9OlM3HnR716Zj1EdAXJQoaHGbnFkzvdhUc2xiJWFq27ze9iAv10wzeXRiSQW9NEnfWrUEEKJ1MNOIVHekU3x4K0guXmoRYPJahQhiR0/B3WAMMdOPIIuHgbNDkpTtw+uUpHjX574GJZsIdXa6J28PL/Haz7COlx7w2bwgGvMk6JHthgkOc5W3sBXx1xEl4F4f4QtDJOVnBejAZWR0R1yH2CX2RZM97zjKzHEaikiesIN+IqWv0Ar1ORQij0bbVq9c0NjdC6AZQnBCi2G0NiGyOuwkW8BDtq1oUz4En7Z3joHtf4kBYVBSprR0fjgTTr5lKD9JDn8K6blglt8F0CP+oq3fnLH7Ju+/dcedPIsVlCEEJIZkCvaaMJElGbG8rbFq2Zdu6ZQOLmJZl2rZtMbKSJKjIiiyzfcboSYqMZLZXmcQiy/QsbJsWfUHoawqtLY233/rD88+bnWk871CQLvqgTFkKSoaFW03s1hB2GYWEfPHFvpKy6qu+c5umKcVhrbQ4XFIcKikOlkYCFImGDvY3tDY0tzU0Rvc3tTU0tzQ0tTY2tVGZUVwcLi8prigvKi8Jl5cVVZZHyktC4YBkY9jclmhuiTc2x1rb4s1tsXhrYv6fHt+4cWPmVvEhIb2Ii4ZAiOXBSatNtsdxOlkC6OyLhvi+a6YJoaUrIB5HqgJUGQdkoAXUaEKP6/G4EY3rMcNM6HrCNA3LNgnGlBAtUzd0RdclIy4nokhXUUAO67oR56AbCXo2/RenBAwwYtWnOZB2HSE96qO2SqlKyc9sNtGmVjtdKwq6rRp+jSNohBdQQEeZYrEvNBG7owJH/hHvYOLukgjcDSc5EPei2OkPz3I9UApIy+4jCoT9NInqxAYDbGyhDxl20YjyVCr0DVXwJyd9OtevW8WByYXGsLNGcEf4+C+YB5M0PbuP2p+Di9hIpiYd19mwxSQs0dHNLedcQnrxPorCESUSNd9jNo5hUtdiTK4MHPLE/2BI1+4jY0ugBkGC17Uva7B60Nd1YKK6fxAdVaJ80qzT94v32v8zLP/12N0I0ktU8n11wem90Se8beOjJnN3wqqhtoyTbXBc10473TkVCtAtVOB76Irdm8V4NgwxFjPzMLF5OzL/R6gRTL/hprCNMODbPbOTnDOFPcQvyuuE+P6rzr2SfCQS0qI+Uf0PzuoTeLguYRHQpIO1zXbvoIQc3MEDu3FOty7AWI9Hg8gaPGhQUUjVAkooGNA0SVUV6kUEgmoVKglqweKIVlVhRGN6LK63xeP0zJCmhUOBSCgQDgYikWA4pAY1egZUFamkJKgGlEg4GCspqk7oW7fsSsSasW2IOEV38TqIKAIjcFwZGhxGG9tIs0k+qLdP7eV4pQeKwMD2qiwwcOCAeKz5lhsu//L550+aMoM6X2LuAxZnQ1FFgKh1zaJMbANfUS8IW/WWllYimg9Y4ARTZ80SMRVebUb5QrVtY+PaD57/059lNTB8zFX8pnPrd6Rl9zk8GZTBlCplU5tB2WzxPuM6Uy1RJSJKbQ7gxXnsPG3a1Lf/+eZ776145bVXnvjNvA2froNKmAAvZU1cY9hNArmXEsEu0VDptPLy7kCHuijvJqJDRo0c0K/mzp/8bMYp03pVVuQhGJk28wLmuqGTq6S1TfCDevx+vbU9Bo5m3aLYI8JUd028v2VlJWeddfqMU0/aum3XzFNOHjF5lhwqpRJPtyyD/jMN6vZTIaZTZw1bNnbdD0JkiKhfrMiKxAIMUOYv6NuAKpnR5o3vv/yLu38+cfy4cCQEHCmc81h4Wmaz26sJzckVqoKkry2PtljWU1tiD5YUieme6ABj6txwHvDcNiq5ysrKKIdGwmElXFxcpMUTxr6GJtlQKc5iegIQG3JdwgkN8X3uJZljTlOYpFSZvEQBhaJPNThDUzFKccc31ebTTHLvd6TXFiOcUgDlYcVgYESaWBf/oB7+4TPjxqPIoAhwsqwkRZAtSYTz46jzx6rIBMVqqlpaVETRxx6ObW/+fK8TDCRIkkBxOKhAmVIljzVApVhWxXg64ohVzHciF5rYySHkxRtKO1wKeW+ODImMyE0jtK+9Z1D/99G66H0TItwusbs8Q4SvWmIN9phLsUH9Kz7esFmYITwW65Y4u9EEpxSffelYNoIfqP6tLi+xLSv/3mO61aWeEcdU3oxeSm2Z8mGT+fLn5pVDrVHUnxPjjg99LYoximYZWBIiksQbB/tWVVPuJKwf0ykb4KRuAaCI8b0AOJYeEWUtDP8wENDGDh8Ya60nsADDaQ+nJZCbGGwJlSq8uH/gkya8NWr/307j9uJgV0NE7a0crEWIsAg9KC0Lq5KsA501lrLeIQEIEpsalsFAgNsnzDwPqqqmyrIslRZHTjvhaAPDpXUbJXrSYSwmM0hP9vG2AzFnlOGJ8u9FgwK/3hzfEQfPbjZvHKmVyF00U1k3OeNObI0fM6RmwGAq4IyEPuvkCYtWfBzbtZ/pC8IUESU7yttDanp9ZfY0wto4GB8XhyIqr7WAFM0mURR5+rEj334xXzPDfJBewIqLfI+vmI8xKExuG629tce6aogWRKIWFqTAoNPCxoZWOWFNCOOJqM2KZBEVmLt2N3z08Q7Kxr1Ky4KKtmH7LgvyYnMCKXtv2rHnnt++yE0/Nmtt0tjRJZEgpb+qsuK2mDGgb1lzcxRi1nAJgNs90W6Edg+voz1MiTqQ2FVDQnMGkYgM3JRYCvIjXs8Hp7pde/ctXLj47399s7i4eObJx1VV9nr5n8t37ttCHV7DsFqiMRsSb1KTeG5ettOyyY7P99RranlJ8bHjhn245rPpk8cauvXis/3uu/f+8847d8rxk4cMHQSc6pvulCpKBURBUEHYGedh85LklI4bswuBbduvvvrGbbfd2qumf3V1r//96S9KyyptYjuWBkF8WBgSFl/yBZxXiM0zZ/MueKkwsCgBawH1rp/e+9xzzz751LN33333LT/44WWXXqwE5Kw38CZBxt3kTs2A5EzdO9DAW+EtI7Dm43X3P/DQt667adpJMwMBKu4ljC0ZsjpBp57CSSodRA1wixBjN7khs9HyyB48ZOhtd9xlmvpHH3742yceHT1yxOTjJ2a4ukNC5oNIkNiOQnA1ONjkXsa5Lyx4ccDgoWef/eW4rgMnMIWI19HGh1Ox+BXVtzh13TYXEM74Kn4BTP2WATVl+/c3NUcTJCCfOH3q2k9WPf7Es5Mn1TIjupuEDFICoz4iRgKB5BxaOwgpRFpbY/98652LvnKFYYscO0Iie+lsDMLzZiKhhmF7QUeH33P0AXb1FwYkGJAkCKuqSmWlLZYw9IQ5ZdrJd97+g5279vbrX9OtmRfw7mjgrTVltMCtqdu+c09rS2t5ZS/iJh29ECvfTIQyoSSb7GEQaAGvc8V7LGLGMsU5QjJlexa6ZZRP/WD+OzioqYg/p/79+0eCkVWrVlP0Zb7Ag0A2Zlg52cQDPmbq8AuismybkqmiKO7nXM+w8AquLi8f1LcPj/vDWDxRt2Vnq6k7Khc4+lPQdQDBsUMHRsJqIBAoKSkaXFOD3MGJsqRADZmWrVEIai0tLbn2QgoweNjjSTcbS9UAGTmsZsVH67fvrqfcSQmrT3VZ447PxbBDBKlBZzNnGrLRpuXFxTv37KNIDWqBEyeMmHjMYK/WyKZ+r42dDG9ac/gOFwoztxmKCSEO9igB4nBIu2T2iXvq2wC0qRfXpuN9jQ2yhCIhjVIutZA5ITI/OaKpjAwlVF4Urh09cE9DmxtKhDrVu7ysCKc7e/5wIX/o82gCelWRgEVALSh2syFV5SW9Kkupl0Hdh6aWxOC+lSEtUFIcEiajE6UX7guPKPQuLwlqCgRRiERDJ4jHjbY4SwFSPIqfyfWiCsm8iEVBqbiDNl8r5qWrnAdZQZBu2BIyDcOE7hY2PKeBiJgfgaBhWwFWpylmALDL6iaOxhM84wbyECsFHbZ6ciMBznwQESwiklNUTQ6qHQ4F0KnlYYwKiTOiFvK0Jy+54oFowKPE1HdlhgxmLixPFTkji0QaCTjxbsgCClAmTNlACYpQONPdfDqnM3kMup5b+uCaYMSp7GTXsXnoTFxNDAH1U5/gLeJEJrHIOkLy8u7EmhY2wgNnNkyZXnhrvdpc+6WFoHJLPUOUJCFFRpYlM3nPf5lwhFHqi8aDlqkqlhSx5fayLGEn88Mozop1HAiY9Y2o1LQCKiU60tSMY3H2RBKm9sXIk9+WB0c364fHwl7eij74ZosNh2MelYiY+fKx/m3unIfLU1p0GYbI685dp0MRWj/sxDPP7/LMdTE++9bniAW2endIkSZ7lWWgPUoQdLJt9ansZ/EZVcckBpjDZ0D6TxS2AYWvTbVn3rCFkOdWth0W9WGR0+euN58NT1zzlIsZL8Hnl33O3CwRTpKgUh7Quc3FUzbUST/8YfKC76Blm9QrCARUqlKBazO7HocfM87WQcIubEduR0BccbMp7dCRKzYBrtOCo3osGAwqEuriGE0/iIoJN2fKLU52HYmFINozCEnocx6zSDTi6dXyGyeJDCxyxFZmdcL05HWbd9xz+w8vvfrG0cMHUVNZC6hUt8ZiOrU2MHTCdPTXqfHW2BLVDTMYUEpLimQ+rlN4cWInIxGaKC8tCoWUz/c29Kos0zTW6PfF/taWNoMSnx5PzHvg5+fOueKMk6YeBvqSqtDFD9MPemnuoAvSiXlFXbszNxtI5SqYVImcj6jNSpIrV9K/IxDabaq7Nw0DsaPDjANCGiiOSM0KicV5eIBZyAyDCcOqj+sx0wwpoDpoKTITGmInA05LYjsK0rsEFoXkrW2oX5lUFKZC3d6ugwaqeBCKEjOyb9vw+K4pldLhPXIX5QS603Kc6GvHkXpJqgP45vm0p/ogyDxu0X4+vxMekELOvkDErU3A7gGY5dOcaXFOcYgTIADuIsRXfvMYOZ60p2yRfNjsAtv/6+ErRRy9YLvFiKILKfUUC4Zd4oZf2k/oeCTMYAJGtqAw6Gt3ex2/zRW87tfEUR+AHNzsKDD2CoU+N0jjuvdODs/51jFBU+CuAwnmqZLgYFC4rZ68eAvoSHqA8y4mLohjU6hPtxerkN3YBd0py8UfF/nQZyYAH/K6hJxD8HjOoHDo40YcCxn4s9teWJmVoVIS5N2vJAXteecQnwLJPxkWDH080MciLgC0D7TxvuUxA+KIN+HkJqld0M75EDjH/BehT4DX/ONUenc0Dx3+FTttFYg9Dw4Ftft45bJTQdCuT0VwiyVA3LgHAZ5h3c2gO1Af7KxYXbLrjhTnh4IbLikIysldJKGuU2Ngd4BCUh/iG2AxDCIo6hQExREeyRPHEKcp153SysDVsx1GHP+3GS6HAp/R7KZ4e6jPD24b7wEioknc2y3lYOGp70A+F/Hxr5t16HYYLDz6ugAZRblzCoVEX5J10sG1IJ2iKZ2jLzm/wUNDwdCHHGfDeeduP+E00CDPJPTGQaQA2PF1AfDZDZk3OUJwQKwQQApNggVFH2FN0G69S3sdARA06JsR1m2hkD6vGxHgb4HLyW7324F8km4FBWZe1zQmfs3gxrLggTxi3/kFtgcLiT4+myD1V9AtHACpcEd4rtfP1/990WbeRSpyGoCIagzg1lBBt5zrgPzbgVYLB4WTfZxkREQeeCzoBv5YGAGhzm3Bzn/8n7vzJwtCgAXWvJ7q8HsWgvZQ0kzoTgErT+8U0HwpDPqQ2EXWSUi6n7reB49CQ55Egp1374FuIhh4CbkDSdDcQwGpz8tFpli8kHkIdMcQqR8Kgz6vFMh2oqCkI2+2D41Ikn5+diZu4RBxsiMH64PLERSI+sSCsVAdTl2wh0G3X6Gj3efYh9DZJM6f2y2cgV3wiIugvGS96UNdt4bCok/87ST9fCafZ/6lKhdyiLKAfnGB0McFHhuh5vc83HifULscxLFexoMkuWjtjnOBoECGi6gTJVR1YJJcHM4gBfN2y9BLgTSva7dhWwzzc405F0UQsamKrCna7/iKqnunDAHwMgTis5px/s2cwso+zIcediY9n9rtgvbw6DL/9Fn4aDPp9E5gT+I+h4gmHFy6ud8WQE0XEH3QJtC2beL5/O2sy1rVeNO4aEzphDs3AeKyroe+fGOwgPV90FdJ0CEV6fAucv5/QKZ0z0zt9+UF8oQ+X0geuE4E4QE/gglOVqvQ6VWFfpQCX2yGfSB0thvscgNeTv+KPwyRS4rMG/WJOgHosJhLcWzQHPRhFjoMCV3rr/1sryuFdLhou9nsjfB0xqFAZ0hdLvGXH/Q5o+Gw6MH3osqsdc9y+oucXiAXi5ALPo/83AScTzw6/3V7P1z6hmIcW54Sv/lAHy8yY0sifIsZNmiPdYUzIkFQxsAWjpmbomRxKllClo0Z8XkdkaIT3/XeMBDb1bCxTRZmL20CLFbGy5o/hR5yB73lEPKBPrYkwLAoETaXr7k1vr+xVYasz7moGJls3CtB7ma8fOIwsSzuk9jQYpuqQG678II+0VvGJvwhgqFu0AcgtbYaCMVibMizJcuKyCRZhqEq8n+G7IPCsx0yqH9IC77zj9fqNq6jXCtB2LdfdUtLa0tLwpnXgpDEV2zxObluYLCdixFqb82XEBJF0fQ0G1uSxLpteacD2LHjs331+0+cOi3XlkyeVIcI5UWKtblzH/zz/D+27dsmTLoN9dsBdKrBk87oiugStCVCDW5DMJODQUX5za9/1a+mOkfL8SBfhgtPYNC1TZ16/HHHTcC56cEgTuyZSQAtoObBhs4b9TmRKMqw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4plEBaIXxBG2pBI6pRUAfGxRKPSv2UkWKSS+4RNlCoyqxg1DQNix+7K43fitAY1zXcQIkj1NuDKSCqRqNddM5EwbU846iBI8i1CoOOIMm8imQ6mNJtOzeIBV/TAVT6EShXie1zMmY5jcrQm+NmGjTEygsSkcO+0hD23ADWimpvSX//6vm9/+z8LhUL4PqVgbGzkH//xnxJ2uuZ7qYTFDWsAVJdlneoLglRp6b5hs2XQSAtTpdcwX+b1qvYcoFb3bcsoTk5UK+Wrr75GHqv+Z4lE8sUvuuylL31JMplYGDYcPqVf3vOrGz/2f0/f+JzuxauEKFGfAvaaZauozwmEiTRPqmwGndQO1S7Sme6KaYtMc81S9RrDvOAwxRo2kCqxZmAjrPNUo1wTjmNh8pnP3Xzk6NF3XfvOea/ueKlGke6/fPqzF154ydkXXL738JgYGyoQhvWSqNrz0/JrZM1YGNGFVEdzZZ2pykgHMLSkJTpEraruZt2gAgaCTjD6fYFttLg3f/45p65avfYLn//0O99xDcYIPHP1EhwPapr3c6VcznXluUg1Ebnzh988cugAo76TcCiFlWpVFupqatCBbZ1sr7ProQ7f6oJbtWqmBVTIzmmI3aBsQZ6BkGjIYRrlcoVzdozMq699v+fXc7ksIVxD8DC257fA1rBhkcIqiTmVTNWrUxvP2rR1y0PvuOat257Y+Z3vfr9nYDGXtYYh8s9MbiQiwTj52lzKuSq/fSpKv32ifvqU8k+5vmMahsEPNkSTFsvgPB1xRBMJnk99vm4x5RqMDg9fdunzr7ryiuuvf8/Fl1z+7W/9ByFukN8Eptvl8aNGsRhB5JQ2a1aAEiS2BOlfvGzvnu2nn3HGRKG0/qzzr3rjNQnHyGWS/F9XLpnPJFJpm+t6xZI/Nl4amyiPFYqjE6WJwtR4oTg1VU2nk935dFdXprcr251L9nRl+7sz2YzF1ZliuV4sVgvFykSxUixVazVy2y039/T2btp0XjKZHly2GiKkCiaB9hTNX1TNk2qO1RqUE5eGDECWpYkiGuLX6zUMjboJ6xasVqFtANvEXCmuVmtc2RdQ4xKs7nmuL//nu0D8WTfrdavuoVrdrFQNLmp8n9XEKRz4OVVxmsdZvKecQFRwNR+IzcuaGHh7UdOs2s0iGrWniQXd5IJjoP7HQJhypRx4dJrnCipRpViJDOdqx4YK0SjlmgaCuuGyCQRaI5srqGSdJ8yTao7FCAzebtwpaCq/0HcZ1PUEh8CZ12hgMdCjw0vC8CqNtYd+Q/1lwdmNKy+0NvyshA5qIqGDmkjooCYS4kONVNuV+h+o/FRkUskiZ0axKARnLKjAZaLLjXDEMPlL/g4iMSJNTTu8ZMaESvASSUhUFQULILpZS+vm8sYbveS6bbk0lk2iFcsHk6KRnJl0TG78maaFEcxluIKPM9lUT3e2Uq1PcT2nUufWuWVZqaSVTjr8lFTSSSftZMKAGJoQ5zIpK2Fn015vV71Sc/cfODJVHOc2PoKtX0iMuXye6204/fQvf+Ur7732T656/RvWbTwHYgvobp6ynhvrJyy7GgkNVvnDqyUwOQEk6TCVvc/CHh0iCk6xDLXseXLLbbd9zfXBae94a92tB9rTyRC9dOv1yy9/wdln33Hvr3/3ox//15c+9/lt27YaTlYmciq3pTJ1tFKnLM+wS8oM95hSJFX7IepWNqxft2LZ0Ic/cuOLL720r6+7UqmI41jLQpcg3g0l3Zv9fT2v+eOX9vfm//2r/7Fj97Zc7xJuaBMRe/GZqIyTzRWobF0k3H2yI5JovKJ9PnzfyRxrblIL96igLwYnx/acufG05z/vole8/I/U8FB1cGtvP8a8Yag8V/LlzTd/Yf/+g8855zncphqZKFargv6ZqQ0E0dgbggP7dvtOFnGzG0G/UhwY6MV2itvlGkmy7Jt/tri3Cy85fdv2Xb9/9LFN5527bPlS1pQ70cIlxJo3rJKL0PDw8M7dez72l/9v8ZIlnL18/j9+/Pj2/ZZh6HwQQRTojBVdX7v5pnJ2tZ3qNm0M9tz/kle9bvMhn+9KpHMZhUdiyUD+hv91BceWY5rvfvc7N2/ZylEjvxBpp1jrsNOOYQG33XZ7f1//okX9hmHILkbAJ6olvmyT74swjJnM9vZ0F/0akJmPSRs76e5yZb/oQBRMM/Sp6N2CDUMcAdE555z3g//64R/90eWtJZYQYs2vET/L5eq/f+Wrr3nt60zL5LtJpAwLi5wGmWhUogLUPLpq1Ypdm4eFcuKVe3ryZc8Q7UswCrL+VE4pUpjyff+ss8755CduHB4e6+vrCb6xlewm7vwa+vtHHz148PC5mzZxTqqcCSqWpnqJKY8up6CJYu3Utaf/4pEfih5ZXqV/6cDIRAlMLwpTznbV94ljYcWqVXYidccdd7z5zX8SfGMr7z9ObZhrL4T84q67Nm7cuHLlKjnAXHRNSKdSjIj6QaUkyyPJ+MTkxjNXOaDGt9pA3urpGRifKGLEQOAdVozJtg0DIZcI72Iul9t0/gXfvv07V1752jgW0FLUBM2BZHcaYRJMTk499OAjr/zj12DDpK4nu4+Ai597hu+6T+49PFWqCc4j9gyaKlezXX2ZpFNgdPTQ/sTGM6ZGXEONHRFxTinnGVi/eimT/edUXtsLX/Tij999544dO1atWi1vgGmqCtvgHAe0DjVQZ59xVmmI3CBkYGtkZHRkdPSSF1zqeZ588FydASsW9V79+pd843u//MV9j3KbQApvVBcedNyTy1RqoxiQTDbvHxg3Eqq1EfMo6O/OvfLS885Yt5L6dZlCLKysDRtO6+3t+/1jm9etWycc1kjn/4GwWeZxQMtQI5P2mIHx4sHB+371M+p7d955Z74739PXV/e8wtSkTsmX+VVcoz1z7cCjj5kTUyWurBBI+dZ74OGtp6w5Ze+ddwyesrbGjQFSdmuqyxlLOeYrXrhx3fLeUqFQAjSI0AGO2TPPOuvue+7mu7NSLj1w373ZXC6TybAQPQueKSFBVJJy1Lz1bW+76W8/uWPPnq98dbdtm1zRfdc1b2skCAOZgSTSyRm3JEtc99N9tdiRx0HSMmzTGh0Z++l//rvv+jqADaBtos9s+yWlui+hTnSUwbtqvVar1u65516+SQ8d2H3Dh/8imcsH7aOOi25ahhrlrGaULFu28uabv1yZKtbdmpIqI2PFUrViYpMvySO+7HorejxyYhFqDiGeR6AcXsONaS6WBQaxkc44ysBCFIju8bZRqVR9lximsWrZYm6aK7tqYrL0+LY9vflsJpPoW7SEeWzzjv3BhAoBJ0LqkWKAXATRqu8NDQ4kUo6KT27ffXiyVDGwcCz4PlFhSKZtSc5HiOuKCVi2jSYnq65ADbOw2duT4ZxXZaZZtp1JOIVi2SeU85MVywbTKVs9i8xkdXjSG+jrSicTIsxHmgtdjkuYtzS/JuiwJwroGBNZUzIFRGixwqXC1y9qLsShTBvXfHv5HuX4QoJ6DHmg7HEjcq6E/0IpQvxtl7/Bf4mVw0D6iBACf0eexP/5sEEsLPwxb2ihhIJhGn0YXtEl/0rLk7ZQIDgUh1SUI4NHGlnBBVRQRucMwDCSEyQQTFPvGiHwIN4CG5GX+UOs9VBRfzRDWFgw4+2Zf7fuvuYKbckbDqLAUrKQYz9qxO5Dwjg2BNjuMu92dj0KSH2GmtpI/wvj6DNIrKlAPOZ7nAZtDbZEPfk5Vhu0mW7iHbimbEcs1WCIdIFPmDKrDa7A5BEpVUFao0qxEodA1bZGBWtiutnZYSHabRxj+MVRHnj80EZe85SLj7STw6q5tkNb514egx3ZHIAFzbCk7Tw7/iB8Vkuop1pe2F5C/bUQaswxEO8QJP2qydib8XmYHK56iTVQd2xOUmw3GgUxh+ia1o9lp25pM8zCO2agIlD9WFirCZ/VzeemQSipVE4khWyG7rfg0F6VT/0Ko4zH76SME9rcly9SG4aN+vhZFJ8FgfbqNcdghjWV9AaeCp2vveA4OhET1p5lvIZqNzZTMRX9QkDTMoNyJx3DDtqQBHHJ8LggNTh8Z3r7Bai/Ude1qtkM6ppIJpyrsWXHy8laUiqmE5tF2yZtDSolDqlkcdYoBVSuGKRax0pPpqxtoKrhQZBWIyvJRExFpt6o5hJQTxUQHlHh8xTeUeH60TPP5XQ2jThxZekhDlLT5ze7qAWokUWlvh7EJ5fKn13N82hFD8VA2DBMJIslqXhBGyMzDKHsiTF8CEHbNj3R4EmQk2Valmky1bFFZB9hIGeGyt6F6MjIxOgEVjNWiOsnkyY/XSQ+SuM9k3agbD4gOt0prM0L5okakUbVZBOtXr367l/c/abVZ2HL2bxtnw68aA4rOomJWw3M66YSB3URJOmIsCnltxErKdfc0cKUwrwytSSaReN83ataFemq8jsIhsfLMh1UeC6waezYcei2227PZDOiumi+GUnzRI2IsDUxy7/6q0+867o/u+1rX1ix+hTqy8EITDpcIPO1o1+1xmoukW/ynMswdlBWp96dsSDd4ieY0xH4S2VaoIkNEdKFqkAT80MnxkYOH9j5T/9wE8Z4foP7wPFsqOba2K5818c++pEvfvFLU+VRGV0UjZUPHTr8+ONb1p12ejqVRoBYYouYlVrN830kEko0vnzPq8gefTYHy2jUUarsAsnbbdPkH9br4lzHtiSVsUq1LqOZZOvjj5966qn9i/pBcHwuBd/9iY9uPOMMMG+aOX5eExb0rFu/7u8+dVPzR3fefd+fX3/9O6+/Yd2py/hhi3tzjm0cHStNlaqhicT58Oh46dDRcY6oxX1dvT1p8ZwZC4pP9aoGejK5jDM2WRkvVE5d0QtFFJTs3DvGj+Fs7kPvu/49H3j/JRc9l+9KCFvWniRGvUbklFNSr7u1Wo0vplZ3LAPVZZmX2i9Q5IZQTgt12SNCFo2ZctxGGIHTv6pVK591VIkYl02GwWmN8D+ByE52iSyybLmrMF6VL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" name="Obrázek12" align="left" hspace="12" width="66" height="114" border="0">


Krok 1

Odstráňte žltý uzáver z injekčnej liekovky so Zomactonom.



Krok 2

Umiestnite adaptér na injekčnú liekovku tak, aby hrot smeroval do stredu liekovky. Pevne zatlačte, kým nezapadne na miesto.

Krok 3 a 4

Odstráňte šedý uzáver z injekčnej striekačky a tiež biely uzáver z adaptéra.

Krok 5

Položte injekčnú liekovku na rovnú plochu a pridržte adaptér. Potom umiestnite injekčnú striekačku na adaptér a pevne zatlačte.

Krok 6

Pomaly stláčajte piest injekčnej striekačky. Dbajte, aby sa všetok roztok dostal do injekčnej liekovky.

Krok 7

Pridržte injekčnú liekovku a pevným pohybom oddeľte injekčnú striekačku od adaptéra. Adaptér zostane na injekčnej liekovke.

Krok 8

Dajte biely uzáver adaptéra späť na adaptér a pevne zatlačte, až kým nezapadne na miesto.

Krok 9

Potom opatrne otáčajte injekčnou liekovkou, kým sa prášok úplne nerozpustí na číry bezfarebný roztok.

Injekčnú liekovku s pripraveným roztokom uchovávajte vo zvislej polohe v chladničke pri teplote 2 °C až 8 °C.


Vyhýbajte sa pretrepávaniu alebo prudkému miešaniu. Ak roztok zostane zakalený alebo obsahuje čiastočky, injekčná liekovka a jej obsah sa musia zlikvidovať. V prípade, že roztok zostáva zakalený po vybratí z chladničky, môže sa zahriať na izbovú teplotu. Ak zákal stále pretrváva, zlikvidujte injekčnú liekovku aj s jej obsahom.



Rozpúšťanie pomocou konektora na prenos rozpúšťadla na použitie s klasickou injekčnou striekačkou



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" 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" name="Obrázek16" align="left" hspace="12" width="55" height="165" border="0">

Krok 1

Odstráňte žltý uzáver z injekčnej liekovky so Zomactonom. Umiestnite konektor na injekčnú liekovku tak, aby hrot smeroval do stredu liekovky. Pevne zatlačte, kým nezapadne na miesto.


Krok 2

Odstráňte šedý uzáver

z injekčnej striekačky.


Krok 3

Položte injekčnú liekovku na rovnú plochu a pridržte konektor. Umiestnite injekčnú striekačku na konektor a pevne zatlačte.

Pomaly stláčajte piest injekčnej striekačky. Dbajte, aby sa všetok roztok dostal do injekčnej liekovky.


Krok 4

Pridržte injekčnú liekovku a pevným pohybom oddeľte injekčnú striekačku od konektora. Konektor zostane na injekčnej liekovke. Umiestnite uzáver na konektor.


Krok 5

Opatrne otáčajte injekčnou liekovkou, kým sa prášok úplne nerozpustí na číry bezfarebný roztok. Injekčnú liekovku s pripraveným roztokom uchovávajte vo zvislej polohe v chladničke pri teplote 2 °C až 8 °C.


Vyhýbajte sa trepaniu alebo prudkému miešaniu. Ak roztok zostane zakalený alebo obsahuje pevné častice, injekčná liekovka a jej obsah sa musia zlikvidovať. V prípade, že roztok zostáva zakalený po vybratí z chladničky, môže sa zahriať na izbovú teplotu. Ak zákal stále pretrváva, zlikvidujte injekčnú liekovku aj s jej obsahom.



Spôsob podávania

Požadovaná dávka Zomactonu 10 mg/ml sa podáva s použitím bezihlového aplikátora ZomaJet Vision X alebo bežnou injekčnou striekačkou.


Presný návod na použitie aplikátora ZomaJet Vision X je uvedený v brožúre, ktorá sa dodáva spolu s aplikátorom.


Ak použijete viac Zomactonu, ako máte

Predávkovanie môže spôsobiť zníženie hladiny cukru v krvi (hypoglykémia) s následným zvýšením hladiny cukru v krvi (hyperglykémia).

Ak vy alebo niekto iný použijete veľmi veľa Zomactonu, vyhľadajte ihneď lekára alebo najbližšiu nemocnicu. Účinky opakovaného predávkovania nie sú známe.


Ak zabudnete použiť Zomacton

Ak vynecháte dávku, neobávajte sa. Pokračujte ako obvykle a vezmite si ďalšiu dávku v čase, v ktorom ju používate.

Nepoužívajte dvojnásobnú dávku, aby ste nahradili vynechanú dávku.

Môže sa u vás objaviť hypoglykémia (nízka hladina cukru v krvi), ktorá môže spôsobiť závraty, zmätenosť a neostré videnie. Hoci sa tým neovplyvní dlhodobý účinok liečby, informujte o tom svojho lekára, ak sa tak stane.


4. Možné vedľajšie účinky


Tak ako všetky lieky, aj tento liek môže spôsobovať vedľajšie účinky, hoci sa neprejavia u každého.


Podkožná injekcia rastového hormónu môže spôsobiť úbytok alebo prírastok tukového tkaniva v mieste vpichu a tiež bodkovité krvácanie do kože a modrinu. Preto sa odporúča miesto vpichu často meniť. V zriedkavých prípadoch sa u pacientov môže objaviť v mieste vpichu bolesť a svrbiaca vyrážka.


Veľmi často hlásené nežiaduce účinky (postihujú viac ako 1 pacienta z 10):

Len dospelí:

  • opuch kvôli zadržiavaniu tekutín, najmä opuch rúk a nôh (edém)

  • mierne zvýšenie cukru v krvi (hyperglykémia)

  • bolesť kĺbov (artralgia)

  • bolesť svalov (myalgia)

  • bolesť hlavy

  • znecitlivenie, tŕpnutie, pálenie (mravčenie) na pokožke (parestézia)


Často hlásené vedľajšie účinky(postihujú 1 až 10 pacientov zo 100):

Deti a dospelí:

  • znížená funkcia štítnej žľazy (hypotyreoidizmus)

  • tvorba protilátok (imunitná reakcia organizmu na rastový hormón, ktorá sa zisťuje krvným testom)

  • zvýšené napätie svalov (hypertónia)

  • reakcie v mieste podania injekcie

  • celková telesná slabosť (asténia)


Len deti:

  • opuch kvôli zadržiavaniu tekutín, najmä opuch nôh a rúk (edém, periférny edém)

  • porucha metabolizmu glukózy (zvýšená hladina cukru v krvi)

  • bolesť kĺbov (artralgia)

  • bolesť svalov (myalgia)

  • bolesť hlavy


Len dospelí:

  • stuhnutie nôh a/alebo ramien

  • sťažené zaspávanie a/alebo časté prebúdzanie (insomnia)


Menej často hlásené vedľajšie účinky(postihujú 1 až 10 pacientov z 1 000)):

Deti a dospelí:

  • málokrvnosť (anémia)

  • zrýchlená srdcová činnosť (tachykardia)

  • točenie hlavy alebo závraty (vertigo)

  • dvojité videnie (diplopia)

  • opuch v oblasti očného pozadia (papiloedém)

  • vracanie, bolesť brucha, plynatosť, nevoľnosť

  • malátnosť

  • nárast alebo zmenšenie tukového tkaniva v mieste vpichu, krvácanie alebo hrčka v mieste vpichu

  • nízke hladiny cukru v krvi (hypoglykémia)

  • vysoké hladiny fosfátu v krvi (hyperfosfatémia)

  • ochabnutie svalov (svalová atrofia)

  • bolesť kostí

  • syndróm karpálneho tunela (porucha citlivosti svalov ruky spôsobená stlačením nervu v oblasti zápästia)

  • zhubné nádory, nádory

  • spavosť (somnolencia)

  • rýchle mimovoľné pohyby očí (nystagmus)

  • zmeny osobnosti

  • únik moču (inkontinencia), krv v moči (hematúria), nadmerná tvorba moču (polyúria), časté močenie, abnormálne výsledky vyšetrenia moču

  • výtok

  • reakcie v mieste podania injekcie (vrátane zmeny tukového tkaniva v mieste vpichu, stenčenia (atrofie) kože, odlupovania kože, žihľavky, nadmerného ochlpenia (hirzutizmus), zhrubnutia (hypertrofie) kože)


Len deti:

  • stuhnutie nôh a ramien


Len dospelí:

  • vysoký krvný tlak (hypertenzia)

  • nadmerné zväčšenie prsníkov (gynekomastia)


Zriedkavo hlásené vedľajšie účinky(postihujú 1 až 10 pacientov z 10 000):

Deti a dospelí:

  • hnačka

  • abnormálne hodnoty vyšetrení obličiek

  • cukrovka (diabetes mellitus typ II)

  • mravčenie alebo necitlivosť v určitých oblastiach tela (neuropatia)

  • hromadenie tekutiny v okolí mozgu (prejavuje sa opakujúcou sa alebo silnou bolesťou hlavy, rozmazaným videním a nevoľnosťou a/alebo vracaním)


Len deti:

  • vysoký krvný tlak (hypertenzia)

  • sťažené zaspávanie a/alebo časté prebúdzanie (insomnia)

  • znecitlivenie, tŕpnutie, pálenie (mravčenie) na pokožke (parestézia)


Veľmi zriedkavo hlásené vedľajšie účinky(postihujú menej ako 1 pacienta z 10 000):

Len deti:

  • leukémia (zdá sa, že jej výskyt nie je častejší ako v bežnej populácii detí)

  • nadmerné zväčšenie prsníkov (gynekomastia)


Hlásenie vedľajších účinkov

Ak sa u vás vyskytne akýkoľvek vedľajší účinok, obráťte sa na svojho lekára alebo lekárnika. To sa týka aj akýchkoľvek vedľajších účinkov, ktoré nie sú uvedené v tejto písomnej informácii pre používateľa. Vedľajšie účinky môžete hlásiť aj priamo prostredníctvom národného systému hlásenia uvedeného v Prílohe V*. Hlásením vedľajších účinkov môžete prispieť k získaniu ďalších informácií o bezpečnosti tohto lieku.

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5. Ako uchovávať Zomacton


Tento liek uchovávajte mimo dohľadu a dosahu detí.


Nepoužívajte tento liek po dátume exspirácie, ktorý je uvedený na označení obalu po EXP. Dátum exspirácie sa vzťahuje na posledný deň v danom mesiaci.


Uchovávajte v chladničke (pri teplote 2 °C – 8 °C).

Uchovávajte vo vonkajšom obale na ochranu pred svetlom.


Po rozpustení prášku v priloženom rozpúšťadle uchovávajte injekčnú liekovku vo zvislej polohe pri teplote 2 °C – 8 °C (v chladničke).

Po rozpustení musí byť roztok použitý do 28 dní. Po uplynutí tejto doby musíte zlikvidovať všetok roztok, ktorý zostane v injekčnej liekovke.

Ak je roztok po vybratí z chladničky zakalený, zahrejte ho na izbovú teplotu. Ak zostáva stále zakalený alebo zmenil farbu, zlikvidujte injekčnú liekovku aj s jej obsahom.


Nelikvidujte lieky odpadovou vodou alebo domovým odpadom. Nepoužitý liek vráťte do lekárne. Tieto opatrenia pomôžu chrániť životné prostredie.


6. Obsah balenia a ďalšie informácie


Čo Zomacton obsahuje

Liečivom je somatropín 10 mg (10 mg/ml po zmiešaní s rozpúšťadlom).

Ďalšie zložky sú:

Prášok: manitol, hydrogénfosforečnan sodný dodekahydrát, dihydrogénfosforečnan sodný dihydrát.

Rozpúšťadlo: voda na injekciu, metakrezol.


Ako vyzerá Zomacton a obsah balenia

Liek obsahuje prášok a rozpúšťadlo na injekčný roztok.

Prášok sa dodáva v injekčnej liekovke a rozpúšťadlo v naplnenej injekčnej striekačke s adaptérom na injekčnú liekovku na použitie s bezihlovým aplikátorom ZomaJet Vision X alebo s konektorom na prenos rozpúšťadla na použitie s klasickou injekčnou striekačkou.

Prášok má bielu až takmer bielu farbu. Po rozpustení v priloženom rozpúšťadle vznikne číry bezfarebný roztok.


Veľkosť balenia:

1 injekčná liekovka s práškom (10 mg somatropínu) a 1 naplnená injekčná striekačka s 1 ml rozpúšťadla

5 injekčných liekoviek s práškom (10 mg somatropínu v každej injekčnej liekovke) a 5 naplnených injekčných striekačiek s 1 ml rozpúšťadla


Na trh nemusia byť uvedené všetky veľkosti balenia.


Držiteľ rozhodnutia o registrácii a výrobca:

Ferring GmbH

Wittland 11

D-24109 Kiel

Nemecko


Ak potrebujete akúkoľvek informáciu o tomto lieku, kontaktujte, prosím, miestneho zástupcu držiteľa rozhodnutia o registrácii:


FERRING Slovakia s.r.o.

BC Aruba, Galvaniho 7/D

821 04 Bratislava

Tel: + 421 2 54 416 010

Fax: + 421 2 54 411 770

E-mail: SK0-Recepcia@ferring.com


Táto písomná informácia pre používateľa bola naposledy aktualizovaná v 10/2013


3


Zomacton 10 mg

Súhrn údajov o lieku

Príloha č.1 k notifikácii o zmene, ev.č.: 2012/03710

Schválený text k rozhodnutiu o zmene, ev.č.: 2012/04490

Schválený text k rozhodnutiu o predĺžení, ev.č.: 2012/06225


SÚHRN CHARAKTERISTICKÝCH VLASTNOSTÍ LIEKU


1. NÁZOV LIEKU


Zomacton 10 mg


2. KVALITATÍVNE A KVANTITATÍVNE ZLOŽENIE


Somatropinum*…………………………………………………10 mg

(10 mg/ml po nariedení)

*Produkovaný bunkami baktérií Escherichia colirekombinantnou DNA technológiou.


Úplný zoznam pomocných látok, pozri časť 6.1.


3. LIEKOVÁ FORMA


Prášok a rozpúšťadlo na injekčný roztok v naplnenej injekčnej striekačke.


Zomacton je biely až takmer biely lyofilizovaný prášok. Rozpúšťadlo v naplnenej injekčnej striekačke je číry bezfarebný roztok.


4. KLINICKÉ ÚDAJE


4. 1 Terapeutické indikácie


Zomacton je určený na dlhodobú liečbu u detí:

  • s poruchou rastu v dôsledku nedostatočnej sekrécie rastového hormónu.

  • u dievčat s Turnerovým syndrómom potvrdeným chromozomálnou analýzou.


U dospelýchje určený na liečbu nedostatku rastového hormónu:

  • pri nedostatku zistenom už v detstve. V tomto prípade má byť pacient opätovne vyšetrený a deficit rastového hormónu sa má potvrdiť dvoma stimulačnými testami.

  • pri nedostatku rastového hormónu vzniknutého v dospelosti pri známom hypotalamo-hypofyzárnom ochorení, kde je dokázaný deficit ďalšieho s ochorením súvisiaceho hormónu, okrem prolaktínu. Deficit má byť dokázaný dvoma rôznymi dynamickými stimulačnými testami, ktoré sa majú vykonať až po začatí adekvátnej substitúcie v ostatných deficitných osiach.


4. 2 Dávkovanie a spôsob podávania


Liečba Zomactonomsa môže uskutočniť len pod dohľadom kvalifikovaného lekára so skúsenosťami v liečbe pacientov s deficitom rastového hormónu.


Dávkovanie a schéma podávania sú individuálne.


Dĺžka liečby, obvykle ide o obdobie niekoľkých rokov, závisí od maximálne dosiahnuteľného liečebného úspechu.


Podkožné podávanie rastového hormónu môže viesť k úbytku alebo prírastku tukového tkaniva v mieste vpichu injekcie. Preto je potrebné miesto vpichu meniť.


Nedostatočná sekrécia rastového hormónu u detí

U detí sa Zomacton obvykle podáva podkožne v dávke 0,17 – 0,23 mg/kg telesnej hmotnosti za týždeň (čo zodpovedá približne 4,9 mg/m2– 6,9 mg/m2telesného povrchu). Táto dávka sa podáva rozdelená v 6 – 7 jednotlivých denných podkožných injekciách (čo zodpovedá dennej injekčnej aplikácii 0,02 –0,03 mg/kg telesnej hmotnosti alebo 0,7 – 1,0 mg/m2 telesného povrchu).

Celková týždenná dávka nemá prekročiť 0,27 mg/kg telesnej hmotnosti (8 mg/m2telesného povrchu), čo zodpovedá každodennej injekčnej aplikácii do 0,04 mg/kg telesnej hmotnosti.


Turnerov syndróm

Pri liečbe Turnerovho syndrómu sa obvykle podáva dávka 0,33 mg/kg telesnej hmotnosti za týždeň (čo zodpovedá 9,86 mg/m2telesného povrchu). Táto dávka sa podáva rozdelená v 6 – 7 jednotlivých denných podkožných injekciách (čo zodpovedá dennej injekčnej aplikácii 0,05 mg/kg telesnej hmotnosti alebo 1,40 – 1,63 mg/m2 telesného povrchu).


Deficit rastového hormónu u dospelých

Počiatočná dávka má byť čo najnižšia. Odporúčaná počiatočná dávka je 0,042 mg/kg/týždeň. Túto dávku možno postupne zvyšovať, nemá však prekročiť dávku 0,084 mg/kg/týždeň.

Vodidlom pre stanovenie optimálnej dávky má byť prípadný výskyt nežiaducich účinkov a hladina IGF-1 v krvnom sére (rastový faktor podobný inzulínu). Pacient má používať najnižšiu účinnú dávku, ktorá sa obvykle s vekom znižuje.


Spôsob prípravy, pozri časť 6.6.


4. 3 Kontraindikácie


Precitlivenosť na somatropín alebo na ktorúkoľvek z pomocných látok.


Somatropín sa nesmie používať pri preukázaní akejkoľvek aktivity nádoru. Pred začatím liečby s rastovým hormónom musia byť intrakraniálne nádory inaktívne a protinádorová liečba musí byť ukončená. Ak sa preukáže rast nádoru, liečba sa má ukončiť. Somatropín sa nemá podávať na podporu rastu u detí s uzatvorenými rastovými štrbinami.


Pacienti s vážnym akútnym ochorením spôsobeným komplikáciami po chirurgickom zákroku na otvorenom srdci, operácii brucha, viacnásobnej úrazovej traume, akútnom respiračnom zlyhaní a podobnými stavmi nesmú byť liečení somatropínom.


U detí s chronickým ochorením obličiek sa má pri transplantácii obličky prerušiť liečba somatropínom.


4. 4 Osobitné upozornenia a opatrenia pri používaní


Maximálna odporúčaná denná dávka sa nemá prekročiť (pozri časť 4.2).


Myozitída je veľmi zriedkavý nežiaduci účinok, ktorý môže súvisieť s konzervačnou prísadou, metakrezolom. V prípade myalgie alebo nadmernej bolesti v mieste podania treba zvážiť, či nejde o myozitídu a pri jej potvrdení sa musí používať Zomacton bez metakrezolu.


Zomacton nie je indikovaný u detí, u ktorých je nedostatočný rast spôsobený geneticky potvrdeným Praderovej-Williho syndrómom s výnimkou prípadov, u ktorých je tiež preukázaná nedostatočná sekrécia rastového hormónu. Boli hlásené prípady spánkového apnoe a náhleho úmrtia po začatí liečby rastovým hormónom u detí s Praderovej-Williho syndrómom, ktoré mali jeden alebo viac z nasledujúcich rizikových faktorov: ťažká obezita, obštrukcia horných dýchacích ciest v anamnéze alebo spánkové apnoe alebo neidentifikovaná infekcia dýchacích ciest.


Boli hlásené zriedkavé prípady benígnej intrakraniálnej hypertenzie. V prípade silnej alebo opakujúcej sa bolesti hlavy, poruchy videnia, nauzey a/alebo vracania sa odporúča oftalmologické vyšetrenie, či nedochádza k edému papily. Ak sa potvrdí edém papily, má sa zvážiť diagnóza benígnej intrakraniálnej hypertenzie a v indikovaných prípadoch sa liečba rastovým hormónom má prerušiť (pozri tiež časť 4.8). V súčasnosti nie je dostatok poznatkov na odporučenie ďalšieho postupu v liečbe rastovým hormónom u pacientov s intrakraniálnou hypertenziou. Ak sa liečba rastovým hormónom znovu začne, je nutné starostlivo sledovať príznaky intrakraniálnej hypertenzie.


U malého počtu pacientov s deficitom rastového hormónu, ktorí boli liečení somatropínom, sa vyskytla leukémia. Táto sa však pozorovala aj u neliečených pacientov. Nepotvrdilo sa, že výskyt leukémie je vyšší u pacientov liečených rastovým hormónom, pokiaľ nemajú predispozíciu k tomuto ochoreniu.


Ako u všetkých liekov s obsahom somatropínu u malého percenta pacientov sa môžu vytvoriť protilátky proti somatropínu. Väzobná kapacita týchto protilátok je nízka a neovplyvňujú rýchlosť rastu. Skúška na protilátky proti somatropínu sa má urobiť u každého pacienta, ktorý neodpovedá na liečbu.


Rastový hormón zvyšuje extratyroidálnu konverziu T4 na T3 a môže takto odkryť začínajúcu sa hypotyreózu. U všetkých pacientov sa má preto sledovať funkcia štítnej žľazy. U pacientov s hypopituitarizmom sa musí pri podávaní somatropínu starostlivo sledovať štandardná substitučná liečba.


Pretože somatropín môže znížiť citlivosť na inzulín, pacienti sa majú sledovať z hľadiska prejavov glukózovej intolerancie. U pacientov s diabetom mellitus bude možno potrebné po začatí liečby somatropínom upraviť dávku inzulínu. Pacienti s diabetom alebo intoleranciou glukózy sa počas liečby somatropínom majú pozorne sledovať. Zomacton sa má tiež opatrne podávať pacientom, v ktorých rodine sa vyskytla dispozícia pre túto chorobu.


U pacientov so sekundárnym deficitom rastového hormónu pri intrakraniálnej lézii sa odporúčajú časté kontroly stavu z hľadiska možnej progresie alebo recidívy základnej choroby. Ak dôjde k progresii alebo recidíve lézie, je potrebné terapiu Zomactonom prerušiť.


U pacientov liečených v minulosti na malígne ochorenia sa odporúča sledovať znaky a príznaky relapsu malígneho ochorenia.


U ktoréhokoľvek dieťaťa sa počas rýchleho rastu môže objaviť skolióza. Počas liečby somatropínom je potrebné monitorovať znaky skoliózy.


U pacientov s endokrinnými poruchami môže dôjsť častejšie k epifyzeolýze hlavice stehennej kosti. Pacientov, ktorí sa liečia Zomactonom a ktorí počas liečby začnú krívať alebo majú bolesti v bedrách alebo kolenách, má lekár adekvátne vyšetriť.


Účinok liečby rastovým hormónom na rekonvalescenciu sa študoval v dvoch placebom kontrolovaných štúdiách, ktoré zahŕňali 522 vážne chorých dospelých pacientov s komplikáciami po operácii na otvorenom srdci, operácii brucha, viacnásobnej úrazovej traume alebo po akútnom respiračnom zlyhaní.

Úmrtnosť bola vyššia (42 % vs. 19 %) u pacientov liečených rastovým hormónom (dávky 5,3 až 8 mg/deň) v porovnaní s tými, ktorí používali placebo. Na základe získaných informácií nemajú byť títo pacienti liečení rastovým hormónom. Nakoľko nie sú dostupné informácie o bezpečnosti substitučnej terapie rastovým hormónom u akútne kriticky chorých pacientov, v týchto situáciách sa musí zvážiť prínos pokračovania liečby oproti potenciálnemu riziku.


Lokálna znášanlivosť po podaní Zomactonu 10 mg/ml bezihlovým aplikátorom ZomaJet Vision X sa študovala pred registráciou v 12-týždňovej štúdii len u detí bielej rasy.


U všetkých pacientov, u ktorých dôjde k vzniku podobného alebo iného akútneho kritického stavu, sa musí zvážiť možný prínos liečby rastovým hormónom oproti potenciálnemu riziku.


4. 5 Liekové a iné interakcie


Súbežná liečba glukokortikoidmi môže potláčať účinok somatropínu na podporu rastu. U pacientov, ktorí zároveň trpia deficitom ACTH, sa má liečba glukokortikoidmi upraviť tak, aby sa zabránilo akémukoľvek inhibičnému účinku na rastový hormón.


Vysoké dávky androgénov, estrogénov alebo anabolických steroidov môžu urýchliť zretie kostí, a tým zhoršiť výsledný vzrast.


Pretože somatropín môže vyvolať stav inzulínovej rezistencie, môže byť potrebné upraviť dávky inzulínu u pacientov s diabetom mellitus, ktorí zároveň dostávajú Zomacton.


Údaje z interakčných štúdií u dospelých pacientov s deficitom rastového hormónu naznačujú, že podávanie somatropínu môže zvýšiť klírens látok metabolizovaných izoenzýmami cytochrómu P450. Klírens látok metabolizovaných prostredníctvom cytochrómu P450 3A4 (napr. pohlavné hormóny, kortikosteroidy, antikonvulzíva a cyklosporín) môže byť zvýšený, čo má za následok zníženie hladiny týchto látok v plazme. Klinický význam tohto zistenia nie je známy.


4. 6 Fertilita, gravidita a laktácia


Reprodukčné štúdie na zvieratách, ktorým sa podával somatropín, nepreukázali zvýšené riziko nežiaducich účinkov na embryo alebo plod.

Nie sú k dispozícii údaje o použití somatropínu počas gravidity u zvierat (pozri časť 5.3 Predklinické údaje o bezpečnosti).

Lieky obsahujúce somatropín sa neodporúča používať počas gravidity a u žien v reprodukčnom veku, ktoré nepoužívajú antikoncepciu.

Nie sú k dispozícii žiadne klinické údaje o používaní somatropínu u dojčiacich žien. Nie je známe, či sa somatropín vylučuje do materského mlieka. Preto pri podávaní liekov s obsahom somatropínu dojčiacim ženám sa odporúča opatrnosť.


4. 7 Ovplyvnenie schopnosti viesť vozidlá a obsluhovať stroje


Lieky obsahujúce somatropín nemajú žiadny vplyv na schopnosť viesť vozidlá a obsluhovať stroje.


4. 8 Nežiaduce účinky


Podkožné podávanie rastového hormónu môže viesť k úbytku alebo prírastku tukového tkaniva a tiež bodkovitému krvácaniu do kože a vzniku modrín v mieste podania injekcie.


Trieda orgánových systémov podľa MedDRA

Veľmi časté 1/10

Časté

1/100 až < 1/10

Menej časté

1/1 000 až < 1/100

Zriedkavé

1/10 000 až < 1/1 000

Veľmi zriedkavé

< 1/10 000

Poruchy krvi a lymfatického systému



anémia



Poruchy srdca a srdcovej činnosti



tachykardia, hypertenzia (u dospelých)

hypertenzia (u detí)


Poruchy ucha a labyrintu



vertigo



Poruchy endokrinného systému


hypotyreoidizmus




Poruchy oka



papiloedém, diplopia



Poruchy gastrointestinálneho traktu



vracanie, bolesť brucha, flatulencia, nevoľnosť

hnačka


Celkové poruchy a reakcie v mieste podania

edém (u dospelých), periférny edém (u dospelých)

edém (u detí), periférny edém (u detí), reakcie v mieste podania, asténia

malátnosť, atrofia v mieste podania, krvácanie v mieste podania, hrčka v mieste podania, hypertrofia



Poruchy imunitného systému


tvorba protilátok




Laboratórne a funkčné vyšetrenia




abnormálne výsledky funkčných skúšok obličiek


Poruchy metabolizmu a výživy

mierna hyperglykémia (u dospelých)

narušená glukózová tolerancia (u detí)

hypoglykémia, hyperfosfatémia

diabetes mellitus typu II


Poruchy kostrovej a svalovej sústavy a spojivového tkaniva

artralgia (u dospelých), myalgia (u dospelých)

artralgia (u detí), myalgia (u detí)

stuhnutosť končatín (u dospelých)

atrofia svalov, bolesť kostí, syndróm karpálneho tunela,

stuhnutosť končatín (u detí)



Benígne a malígne nádory, vrátane nešpecifikovaných novotvarov (cysty a polypy)



malígne nádory, nádory


leukémia (u detí)

Poruchy nervového systému

bolesť hlavy (u dospelých), parestézia (u dospelých)

bolesť hlavy (u detí), hypertónia, nespavosť (u dospelých)

somnolencia, nystagmus

neuropatia, zvýšený intrakraniálny tlak, nespavosť (u detí), parestézia (u detí)


Psychické poruchy



poruchy osobnosti



Poruchy obličiek a močových ciest



inkontinencia moču, hematúria, polyúria, časté močenie/ polakizúria, abnormálne výsledky vyšetrenia moču



Poruchy reprodukčného systému a prsníkov



výtok, gynekomastia (u dospelých)



gynekomastia (u detí)

Poruchy kože a podkožného tkaniva



lipodystrofia, atrofia kože, exfoliatívna dermatitída, urtikária, hirzutizmus, hypertrofia kože




Protilátky proti somatropínu: Somatropín je bielkovina a môže spôsobiť zvýšenú tvorbu protilátok. Protilátky sa našli u istého percenta liečenej populácie, v závislosti od použitého lieku. Ich väzobná kapacita a titre sú vo všeobecnosti nízke bez klinických následkov. No ak pacient neodpovedá na liečbu, je potrebné vyšetriť protilátky proti somatropínu.


Leukémia: U detí s nedostatkom rastového hormónu, z ktorých niektoré boli liečené somatropínom, boli hlásené prípady leukémie (veľmi zriedkavo). Tieto prípady sú zahrnuté do pozorovaní po uvedení lieku na trh. Nepreukázalo sa zvýšené riziko leukémie u detí, ktoré nemali predispozičné faktory k tomuto ochoreniu.


U detí liečených rastovým hormónom bola hlásená epifyzeolýza hlavice stehennej kosti a Leggova-Calvého-Perthesova choroba. Epifyzeolýza hlavice stehennej kosti sa vyskytuje častejšie u detí s endokrinologickými poruchami a Leggova-Calvého-Perthesova choroba sa vyskytuje častejšie v prípade malého vzrastu. Nie je známe, či sa tieto dve choroby vyskytujú častejšie u detí liečených somatropínom ako v bežnej populácii. Ak pacient kríva, pociťuje bolesť v bedrovej oblasti a/alebo bolesť kolien musí sa zvážiť ich diagnóza.


Ostatné nežiaduce účinky súvisia s liekovou skupinou, ako hyperglykémia spôsobená zníženou citlivosťou na inzulín, zníženie hladiny voľného tyroxínu a možný vývoj benígnej intrakraniálnej hypertenzie.


Hlásenie podozrení na nežiaduce reakcie

Hlásenie podozrení na nežiaduce reakcie po registrácii lieku je dôležité. Umožňuje priebežné

monitorovanie pomeru prínosu a rizika lieku. Od zdravotníckych pracovníkov sa vyžaduje, aby hlásili

akékoľvek podozrenie na nežiaduce reakcie prostredníctvom národného systému hlásenia uvedeného

v Prílohe V*.


4. 9 Predávkovanie


Odporúčaná dávka Zomactonu sa nemá prekračovať.


Hoci nie sú známe žiadne prípady predávkovania Zomactonom, akútne predávkovanie môže viesť k počiatočnej hypoglykémii s následnou hyperglykémiou.


Účinky dlhodobého opakovaného podávania Zomactonu v dávkach presahujúcich odporúčané dávky nie sú známe. Avšak je možné, že toto podávanie môže vyvolať podobné príznaky ako pri nadbytku ľudského rastového hormónu (napr. akromegáliu).


5. FARMAKOLOGICKÉ VLASTNOSTI


5. 1. Farmakodynamické vlastnosti


Farmakoterapeutická skupina:hormóny, somatropín a analógy

ATC kód:H01AC01


Rastový hormón v Zomactoneje identický s ľudským rastovým hormónom hypofýzy (pit-hGH) v aminokyselinovej sekvencii, dĺžke reťazca (191 aminokyselín) a farmakokinetickom profile. Možno preto očakávať rovnaké farmakologické účinky ako v prípade endogénneho hormónu.


Kostrový systém

Rastový hormón podporuje u človeka celkový proporcionálny rast dlhých kostí. Po exogénnom podávaní Zomactonu sa dokázal zvýšený lineárny rast u detí s potvrdeným nedostatkom pit-hGH. Merateľný výškový prírastok po podávaní Zomactonu je dôsledkom pôsobenia na štrbiny epifýzy dlhých kostí. U detí, ktoré majú nedostatok zodpovedajúceho množstva pit-hGH, Zomacton spôsobuje urýchlenie rastu a zvýšenie koncentrácie IGF-I (inzulínový rastový faktor/somatomedín-C), ktorá je podobná ako koncentrácia zistená po terapii pit-hGH. Pozoroval sa tiež vzostup koncentrácie alkalickej fosfatázy v krvnom sére.


Ostatné orgány a tkanivá

V dôsledku pôsobenia rastového hormónu dochádza k rastu ostatných tkanív úmerne s celkovým zvyšovaním telesnej hmotnosti. Zmeny zahŕňajú zvýšený rast spojivových tkanív, kože a väziva, zväčšovanie kostrových svalov so zvyšovaním počtu a veľkosti buniek, rast týmusu, zväčšenie pečene so zvýšenou bunkovou proliferáciou, mierne zväčšenie gonád, nadobličiek a štítnej žľazy.

V súvislosti so substitučnou terapiou rastovým hormónom nebol hlásený disproporcionálny rast kože, plochých kostí či urýchlenie pohlavného dospievania.


Metabolizmus bielkovín, uhľohydrátov a lipidov

Rastový hormón vyvoláva retenciu dusíka a zvyšuje transport aminokyselín do tkanív. Obidva procesy zosilňujú syntézu bielkovín. Využitie uhľohydrátov a lipogenéza sú rastovým hormónom potlačené. Vo vysokých dávkach alebo pri absencii inzulínu pôsobí rastový hormón ako diabetogénny agens vyvolávajúci účinky typické pre hladovanie (intolerancia karbohydrátov, inhibícia lipogenézy, mobilizácia tukov a ketóza).


Metabolizmus minerálnych látok

V dôsledku liečby rastovým hormónom dochádza k retencii sodíka, draslíka a fosforu. Zvýšenie strát vápnika obličkami je kompenzované zvýšením jeho absorpcie v črevách. Koncentrácia vápnika v sére sa u pacientov liečených Zomactonom alebo pit-hGH výrazne nemení. Po podávaní Zomactonu a pit-hGH sa pozorovala zvýšená koncentrácia anorganických fosfátov v sére. Hromadenie týchto minerálnych látok signalizuje ich zvýšenú potrebu počas tkanivovej syntézy.


5. 2 Farmakokinetické vlastnosti


24 zdravým dobrovoľníkom sa podávala dávka 1,67 mg somatropínu ako klasická podkožná injekcia alebo im bol somatropín podávaný pomocou bezihlového aplikátora ZomaJet Vision. Maximálna plazmatická koncentrácia 20 ng/ml sa dosiahla 3,5 až 4 hodiny po podaní lieku.


5. 3 Predklinické údaje o bezpečnosti


Toxicita jednorazovej dávky

Štúdie toxicity po podaní jednorazovej dávky sa vykonávali na potkanoch (intramuskulárna dávka 10 mg/kg), psoch a opiciach (intramuskulárna dávka 5 mg/kg, čo zodpovedá 50 – 100 násobku terapeutickej dávky u človeka). U žiadneho zvieracieho druhu sa nezistila toxicita v súvislosti s liekom.


Toxicita opakovanej dávky

Žiadne príznaky toxicity sa nepozorovali v štúdii na potkanoch, keď sa zvieratám podávali dávky 1,10 mg/kg/deň počas 30 dní a 0,37 mg/kg/deň počas 90 dní.


Reprodukčná toxicita, mutagénny a karcinogénny potenciál

Somatropín získaný z geneticky modifikovaných mikroorganizmov má rovnaké biologické vlastnosti ako endogénny ľudský hypofyzárny rastový hormón. Obvykle sa podáva vo fyziologických dávkach, preto sa nepovažovalo za nevyhnutné vykonávať toxikologické štúdie v plnom rozsahu. Nežiaduci účinok na reprodukčné orgány a na priebeh tehotenstva a laktácie je nepravdepodobný a tiež sa nepredpokladá žiaden karcinogénny účinok. Štúdie mutagenity nepreukázali žiadne mutagénne účinky.


6. FARMACEUTICKÉ INFORMÁCIE


6. 1 Zoznam pomocných látok


Prášok

Manitol

Hydrogénfosforečnan sodný dodekahydrát

Dihydrogénfosforečnan sodný dihydrát


Rozpúšťadlo

Metakrezol

Voda na injekciu


6. 2 Inkompatibility


Nevykonali sa štúdie kompatibility, preto sa tento liek nesmie miešať s inými liekmi.


6. 3 Čas použiteľnosti


2 roky

Po nariedení sa musí roztok uchovávať v chladničke (pri teplote 2 oC – 8 oC) maximálne 28 dní.

Po nariedení uchovávajte injekčné liekovky vo zvislej polohe.

6. 4 Špeciálne upozornenia na uchovávanie


Uchovávajte v chladničke (pri teplote 2 oC – 8 oC); uchovávajte vo vonkajšom obale na ochranu pred svetlom.

Podmienky na uchovávanie nariedeného lieku sú uvedené v časti 6.3.


6. 5 Druh obalu a obsah balenia


  • Prášok: Injekčná liekovka (sklo typ I) uzatvorená gumenou zátkou (halobutylový polymér) s hliníkovou objímkou a plastovým viečkom.

  • Rozpúšťadlo: Naplnená injekčná striekačka (sklo typ I) s ochranným gumeným krytom (halobutylový polymér) a gumeným piestom (halobutylový polymér).

  • Adaptér na injekčnú liekovku na použitie s bezihlovým aplikátorom ZomaJet Vision X alebo konektor na prenos rozpúšťadla na použitie s klasickou injekčnou striekačkou.

  • Bezihlový aplikátor ZomaJet Vision X (nie je súčasťou balenia).


Veľkosť balenia: 1, 5.


Na trh nemusia byť uvedené všetky veľkosti balenia.


6. 6 Špeciálne opatrenia na likvidáciu a iné zaobchádzanie s liekom


Riedenie

Prášok sa má riediť len pomocou priloženého rozpúšťadla v injekčnej striekačke.

Podrobné informácie ohľadom riedenia sú uvedené v písomnej informácii pre používateľa.


Pri riedení sa majú dodržiavať zásady správnej praxe, najmä čo sa týka dodržiavania aseptických podmienok.


Všeobecné pokyny ohľadom riedenia sú nasledovné:

  1. Pred podaním si umyte ruky.

  2. Odstráňte žltý uzáver z injekčnej liekovky.

  3. Pretrite vrchnú časť injekčnej liekovky antiseptickým roztokom, aby sa zabránilo kontaminácii obsahu liekovky.

  4. Vložte adaptér alebo konektor na injekčnú liekovku tak, aby hrot smeroval do stredu liekovky. Pevne zatlačte, kým nezapadne na miesto. Odstráňte uzáver z adaptéra.

  5. Vezmite naplnenú injekčnú striekačku. Odstráňte z nej šedý uzáver. Vložte injekčnú striekačku do adaptéra/konektora a pomaly vstreknite rozpúšťadlo do liekovky tak, aby prúd rozpúšťadla smeroval proti stene liekovky, a tým nedošlo k speneniu roztoku.

  6. Vložte uzáver adaptéra/konektora späť na adaptér/konektor.

  7. Opatrne otáčajte injekčnou liekovkou, kým sa prášok úplne nerozpustí. Nepretrepávajte, pretože to môže spôsobiť denaturáciu liečiva.

  8. Ak je roztok zakalený alebo obsahuje pevné častice, nesmie sa použiť. Ak je roztok zakalený po ochladení, injekčná liekovka sa môže zahriať na izbovú teplotu. Ak i naďalej zostáva zakalený, injekčná liekovka aj s jej obsahom sa musí zlikvidovať.

Po nariedení má vzniknúť číry bezfarebný roztok.


Spôsob podávania

Požadovaná dávka Zomactonu 10 mg/ml sa podáva pomocou bezihlového aplikátora ZomaJet Vision X alebo klasickej injekcie.

Osobitné pokyny na použitie ZomaJet Vision X sú uvedené v brožúre dodávanej s aplikátorom.


Všetky nepoužité lieky alebo odpad vzniknutý z liekov majú byť zlikvidované v súlade s národnými požiadavkami.


7. DRŽITEĽ ROZHODNUTIA O REGISTRÁCII


Ferring GmbH

Wittland 11

D–24109 Kiel

Nemecko


8. REGISTRAČNÉ ČÍSLO

56/0067/08-S


9. DÁTUM PRVEJ REGISTRÁCIE/ PREDĹŽENIA REGISTRÁCIE


Dátum prvej registrácie: 28.02.2008

Dátum posledného predĺženia registrácie:


  1. DÁTUM REVÍZIE TEXTU

Október 2013


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Zomacton 10 mg